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Obesity Drug Discovery: Success and Challenges for a New Pharmaceutical Market
Decision Resources, Inc., June 2005, Pages: 18

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Introduction
Obesity and Related Comorbidities
Mechanisms Underlying Food Intake and Obesity
Mechanisms Underlying Obesity-Related Comorbidities
Drugs to Treat Obesity
Investigational Obesity Drugs and Points of Drug Intervention
Obesity Platform-Based Drug Discovery Alliances
Directions in Obesity R&D
Outlook
Table 1. Select Targets That Regulate Appetite
Table 2. Select Obesity Drugs in Clinical Trials
Table 3. Select Drug Targets That Regulate Lipid Metabolism
Table 4. Select Drug Targets That Regulate Adipocytes or Their Signals
Table 5. Select Drug Discovery Alliances Targeting Obesity
Figure 1. Systems Involved with Controlling Appetite
Figure 2. Metabolic Pathways and Enzymes Involved in the Synthesis of Fat and Fatty Acids




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