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Veterinary Health Markets
TriMark Publications, Dec 2008, Pages: 303
1. Overview 7
1.1 Objective of Report 7
1.2 Scope of Report 7
1.3 Methodology 8
1.4 Executive Summary 9
2. Veterinary Biological Products 11
2.1 Overview of Health Products Market 11
2.1.1 World Products Markets 11
2.1.2 U.S. Animal Health Products Market 14
2.1.3 European Animal Health Markets 15
2.1.4 Asian Animal Health Products Markets 16
2.1.5 Rest of World 23
2.1.6 World Market Share 23
2.1.7 Common Animal Diseases 24
2.1.8 Companion Animals 54
2.2 Veterinary Vaccines 57
2.2.1 Major Canine Vaccines 59
2.2.2 Major Feline Vaccines 61
2.3 Agricultural Animals 67
2.3.1 Major Cattle Vaccines 69
2.3.2 Major Poultry Vaccines 74
2.3.3 Major Sheep Vaccines 81
2.3.4 Major Swine Vaccines 84
2.3.5 Horses 89
2.4 Trends in the Biologicals Market 92
2.5 Nutraceuticals 94
2.5.1 Nutraceutical Market for Companion Animals 94
2.6 OTC Animal Health Global Market Opportunity 98
3. Veterinary Pharmaceutical Products 99
3.1 Overview 99
3.1.1 Pharmaceutical Products for Dogs and Cats 104
3.1.1.1 Antiparasitics 108
3.1.1.2 Antibiotics 110
3.1.1.3 Anti-Inflammatories 114
3.1.1.4 Chronic Care Products 117
3.1.1.5 Cardiovasculars 117
3.1.1.6 GI Products 118
3.1.1.7 Endocrine Products 118
3.1.1.8 Anti-Infectives 119
3.1.1.9 Behavior Modifiers 120
3.1.1.10 Anthelminitics 120
3.1.1.11 Antifungals 121
3.1.1.12 Cancer and Chemotherapy in Companion Animals 121
3.1.2 Pharmaceutical Products for Agricultural Animals 131
3.1.2.1 Antiparasites 131
3.1.2.2 Antibiotics 132
3.1.2.3 Insecticides 133
3.2 Leading Products and Competitors 134
3.2.1 Elanco 134
3.2.2 Novartis 135
3.2.3 Alpharma 136
3.2.4 Wyeth 138
3.2.5 Pfizer Animal Health 138
3.3 Veterinary Pharmaceutical Market Trends 139
3.4 Companion-Animal Crossover Products 140
3.5 Generics in the Animal Health Sector 141
4. Veterinary Feed Additive Products 142
4.1 Overview 142
4.2 U.S. Feed Additives Market 147
4.3 Leading Feed Additives and Competitors 147
4.4 Feed Additives Market Trends 149
4.4.1 Livestock Performance Enhancers 150
4.5 Pet Food Additives and Contaminants 152
4.5.1 Pet Deaths 153
4.5.2 The FDA Response 153
5. Veterinary Diagnostic Test Products 154
5.1 Introduction 154
5.2 Veterinary Diagnostic Market Size and Growth Rates 156
5.2.1 Market Drivers 159
5.2.2 Immunodiagnostic and Nucleic Acid Testing Markets 159
5.2.2.1 Market Size and Growth 159
5.2.3 Technological Developments in the Diagnostic Industry 159
5.3 Competitive Situation 161
5.4 Estimate of Units Sold and Pricing 162
5.5 PCR Applications for Veterinary Use 162
5.6 Companion-Animal Diagnostics 166
5.6.1 Feline Leukemia Virus 166
5.7 Agricultural Animal Diagnostics 167
5.8 U.S. Diagnostic Test Market 168
5.9 Leading Competitors in Diagnostic Testing 169
5.10 Veterinary Diagnostic Market Trends 172
5.11 Collaborative Licensing 173
5.12 BSE Diagnostic Tests 173
5.13 West Nile Virus Diagnostic Tests 174
5.14 Avian Flu Diagnostic Tests 174
6. Overview of the Veterinary Health Market 175
6.1 Regulatory Environment 175
6.1.1 International Bodies for Regulation of Animal Health Products 176
6.1.1.1 Regulation of Animal Health Products in the E.U. 178
6.1.1.2 Regulation of Animal Health Products in the U.S. 180
6.1.1.3 Regulation of Animal Health Products in Japan 181
6.1.2 Proposed Regulation of Animal Antibiotics 182
6.2 The European Animal Health Industry 183
6.2.1 Trends Driving Demand 183
6.2.1.1 European, International and U.S. Oversight of Veterinary Medicines 183
6.2.1.2 Antibiotic Usage 184
6.3 Mergers and Acquisitions 184
6.4 New Product Launches 186
6.5 Bioterrorism and Foodborne Pathogens?WHO Guidelines 187
6.5.1 The U.S. Bioterrorism Preparedness and Response Act, 2002 188
6.6 Generic Products 188
7. Emerging Markets 191
7.1 Biotechnology and Veterinary Health 191
7.1.1 Biotechnology and Biologics 191
7.1.1.1 Recombinant DNA Vaccines 191
7.1.1.2 Plant-derived Vaccines 192
7.1.2 DNA Probes 192
7.1.3 Biotechnology and Pharmaceuticals 193
7.1.3.1 Immunodiagnostic Applications 193
7.1.3.2 Growth Enhancers 194
7.2 Impact of Genomics on Veterinary Health 194
7.2.1 Autosomal Dominant Traits 197
7.2.2 X-Linked Traits 197
7.2.3 Autosomal Recessive Traits 198
7.2.4 Current DNA Testing in Animals 199
7.2.5 Direct DNA Testing: Mutation-based Tests 200
7.2.6 Indirect DNA Testing: Linkage-based or Marker-Based Tests 200
7.3 Companion-Animal Markets 200
7.4 Alternative Medicine in Veterinary Practice 201
7.5 Generics in the Animal Health Market 201
7.6 Pet Insurance 207
7.7 Orthotics and Prosthetics for Animals 209
7.8 Pet Cloning 211
8. Company Profiles 212
8.1 Abaxis, Inc. 212
8.2 Abbott Laboratories 214
8.3 Adiagene 215
8.4 Agricultural Research Service 215
8.5 Alpharma, Inc. 216
8.6 Avian Biotech 218
8.7 BASF 218
8.8 Bayer Animal Health 219
8.9 Biobest Laboratories 220
8.10 BioVet, Inc. 221
8.11 Boehringer Ingelheim Corp. 222
8.12 CEVA Santé Animale 222
8.13 Cypress Diagnostics 224
8.14 Dabaco Viet Nam Corporation 225
8.15 DayMoon Industries, Inc. 225
8.16 Dow AgroSciences LLC 226
8.17 Dupont Qualicon 226
8.18 Egyptian International Pharmaceutical Industries Company 227
8.19 Elanco Animal Health 227
8.20 Eurofins Medigenomix GmbH 228
8.21 Fort Dodge Animal Health 228
8.22 Gene Check, Inc. 229
8.23 Heska 230
8.24 Huvepharma 232
8.25 IDEXX Laboratories, Inc. 232
8.26 Intervet/Schering-Plough Animal Health 235
8.27 IWAKI & Co., Ltd. 235
8.28 Janssen Pharmaceutica 236
8.29 Laboklin 237
8.30 Medika d.d. 237
8.31 Merial 237
8.32 MetaMorphix, Inc. 238
8.33 Microbix Biosystems, Inc. 240
8.34 Momina krepost AD Veliko Tarnovo 240
8.35 Monsanto 240
8.36 Mosaic Company 241
8.37 Neogen Corporation 242
8.38 Novartis Animal Health 244
8.39 OptiGen 245
8.40 Orion Corporation 246
8.41 PETCO Animal Supplies, Inc. 247
8.42 PetSmart, Inc. 248
8.43 Pfizer Animal Health 249
8.44 Phylaxia Pharma NyRt. 255
8.45 Sanofi-Aventis 255
8.46 Schering-Plough Animal Health Corporation 256
8.47 Skystar Bio-Pharmaceutical Company 257
8.48 Sunwin International Nutraceuticals 257
8.49 Synbiotics Corporation 257
8.50 Teva Pharmaceutical Industries Ltd. 258
8.51 The Arab Pesticides and Veterinary Drugs Mfg. Co. 259
8.52 ThermoGenesis Corp. 260
8.53 VCA Antech, Inc. 260
8.54 Velefarm ad Beograd 262
8.55 Veterinarski Zavod Subotica ad Subotica 262
8.56 Vétoquinol 262
8.57 Virbac SA 262
8.58 WooGene B&G Co., Ltd 263
8.59 Wyeth 263
9. Business Trends in the Industry 265
9.1 Animal Health Additive Growth Trends 265
9.2 Move to Complete Product Portfolio 265
9.3 Reduced Antibiotic Usage in Animal Feeds 265
9.4 European Animal Health Industry 265
9.5 Licensing and Partnership Opportunities in Animal Health R&D 266
10. Company Directory 267
Appendix 1: Dosages for Selected Drugs Alphabetical Listing 276
Appendix 2: Trade Names 289
Appendix 3: Abbreviations 301
INDEX OF FIGURES
Figure 2.1: Global Animal Health Market by Product Category, 2007 11
Figure 2.2: Worldwide Sales of Animal Health Products by Product Class, 2007 12
Figure 2.3: Worldwide Animal Health Industry Revenues by Species, 2007 13
Figure 2.4: Worldwide Animal Health Products Market by Region, 2007 13
Figure 2.5: Market Share for the Top Ten Animal Health Companies, 2007 14
Figure 2.6: U.S. Companion Animal Healthcare Products Share of Overall Animal Health Product Sales, 2007 15
Figure 2.7: Pet Population in Japan, 1996 and 2006 17
Figure 2.8: Swine Population in Japan, 2006-2008 18
Figure 2.9: Cattle Population in Japan, 2006-2008 19
Figure 2.10: The Indian Biologicals Industry by Product Category, 2007 21
Figure 2.11: South African Animal Health Market by Product Category, 2007 23
Figure 2.12: Global Incidence of Avian H5N1, 2008 76
Figure 2.13: Global incidence of Equine Herpesvirus Type 1, 2008 89
Figure 2.14: Global Outbreaks of Equine Viral Arteritis, 2008 92
Figure 3.1: Animal Health Product Sales in the U.S., 2005-2014 103
Figure 3.2: Expenditure on Pets in Australia by Pet Type, 2005 108
Figure 3.3: Pet care Expenditure in Australia by Category, 2005 108
Figure 3.4: The European Parasiticide Market by Product Category, 2007 110
Figure 3.5: Growth in Global Sales of Antibiotic Products, 2005-2012 132
Figure 3.6: Novartis Animal Health Division: Business Split, 2007 135
Figure 3.7: Novartis Animal Health Division: Product Split, 2007 136
Figure 3.8: Novartis Animal Health Division: Sales by Geographic Region, 2007 136
Figure 4.1: Global Market for Livestock Performance Enhancers, 2006 152
Figure 5.1: Growth of the Lateral Flow Diagnostic Tests in the Veterinary Market, 2005-2015 160
Figure 7.1: The U.S. Market for Companion Animal Pharmaceuticals, 2007 201
Figure 7.2: U.S. Companion Animal Pharmaceuticals: Percentage of New Generics, 2007 204
Figure 7.3: U.S. Market for FDA-approved Pharmaceuticals for Companion Animals, 2007 205
LIST OF TABLES
Table 2.1: World Market for Animal Health Products, 2002-2012 11
Table 2.2: Global Sales of Animal Health and Nutrition Products, 2004-2012 12
Table 2.3: Worldwide Animal Health Products Market by Region, 2007 13
Table 2.4: U.S. Animal Health Product Sales, 2005-2014 14
Table 2.5: Animal Health Market: Sales Statistics-Europe, 2007 15
Table 2.6: E.U. Animal Health Market, 2004-2014 16
Table 2.7: Japanese Animal Health Market, 2000-2012 17
Table 2.8: Chinese Animal Health Products Market, 2005-2012 19
Table 2.9: Indian Animal Health Market, 2003-2010 20
Table 2.10: Institutions Involved in Manufacturing Vaccines and Other Biological Products for Livestock 22
Table 2.11: Worldwide Animal Health Product Sales for Leading Producers, 2007 23
Table 2.12: Common Animal Diseases 25
Table 2.13: Cattle Diseases 25
Table 2.14: Sheep and Goat Diseases 26
Table 2.15: Equine Diseases 26
Table 2.16: Swine Diseases 26
Table 2.17: Avian Diseases 27
Table 2.18: Fish Diseases 27
Table 2.19: Other Veterinary Diseases 27
Table 2.20: Leading Companion-Animal Prescription Drugs by Sales, 2007 55
Table 2.21: Worldwide Veterinary Vaccine Market, 2005-2012 57
Table 2.22: U.S. Veterinary Vaccine Market, 2004-2013 58
Table 2.23: Second-Generation Licensed/Commercialized Veterinary Viral Vaccines 59
Table 2.24: Canine Vaccinations 61
Table 2.25: Dog Vaccine Price List 61
Table 2.26: American Association of Feline Practitioners 2006 Feline Vaccination Guidelines: Summary of Vaccination in General Practice. 62
Table 2.27: Recently Commercialized Veterinary Bacterial Vaccines 67
Table 2.28: Available Veterinary Live Protozoal Vaccines 68
Table 2.29: Available Veterinary Killed/Subunit Protozoal Vaccines 68
Table 2.30: Commercialized Reproduction Control Vaccines 68
Table 2.31: Global Market for Nutraceutical in Companion Animals, 2005-2012 97
Table 3.1: Veterinary Drugs Listed by Therapeutic Class 99
Table 3.2: Sales of Pharmaceutical Products for Animal Health in the U.S., 2000-2008 104
Table 3.3: Number of Dogs in the U.S., 1996-2008 105
Table 3.4: Number of Pet Dogs by Geographical Region, 2008 105
Table 3.5: Number of Cats in the U.S., 1996-2008 105
Table 3.6: Number of Pet Cats by Geographical Region, 2008 105
Table 3.7: U.S. Spending on Pet Care, 1996-2008 105
Table 3.8: American Veterinary Specialists 106
Table 3.9: Companion-Animal Products Sales, 2008 106
Table 3.10: U.S. Antiparistic Animal Health Product Sales, 2005-2012 109
Table 3.11: Global Antiparistic Animal Health Product Sales, 2005-2012 109
Table 3.12: Worldwide Sales of Animal Health Antibiotics, 2005-2012 111
Table 3.13: U.S. Volume of Animal Health Antibiotics Used, 2000-2006 111
Table 3.14: U.S. Sales of Animal Health Antibiotics, 2005-2012 111
Table 3.15: European Sales of Animal Health Antibiotics, 2005-2012 112
Table 3.16: Common Veterinary Anti-Inflammatories 115
Table 3.17: U.S. Pet Anti-Inflammatory Market, 2003-2012 115
Table 3.18: Retail Pricing of Rimadyl 115
Table 3.19: EtoGesic Pricing 116
Table 3.20: Therapy for Various Pet Cancers 122
Table 3.21: Mechanisms of Action, Indications and Toxicities of Selected Antineoplastic Agents 125
Table 3.22: Treatment Options for Canine or Feline Lymphomas 127
Table 3.23: Chemotherapeutic Agents Commonly Used in Veterinary Medicine, and the Associated Risks 129
Table 3.24: Bacterial and Protozoal Threats to Poultry 133
Table 3.25: Bacterial and Protozoal Threats to Pigs 133
Table 3.26: Elanco Veterinary Products Summary 134
Table 3.27: Wyeth Fort Dodge Animal Health Products 138
Table 4.1: Global Sales of Feed Additives for Animal Health, 2005-2014 142
Table 4.2: Target Species and Brand Names for Probiotics 146
Table 4.3: Feed Additives?Antimicrobials and Growth Promotants 148
Table 4.4: Feed Additives?Anthelmintics 148
Table 4.5: U.S. Beef Exports, 2002-2007 148
Table 4.6: Retail Equivalent Value of U.S. Beef Industry, 2002-2007 148
Table 4.7: U.S. Revenues from Animal Agriculture by State, 2006 149
Table 4.8: Use of Antibiotics as Growth Promotants 150
Table 4.9: Global Market for Livestock Performance Enhancers, 2004-2010 151
Table 5.1: Veterinary Diagnostics World Market, 2005-2012 156
Table 5.2: Veterinary Immunodiagnostic Testing World Markets, 2005-2012 159
Table 7.1: Labs that Perform Canine DNA Testing 197
Table 7.2: DNA (Mutation) Tests for Canine Inherited Diseases 198
Table 7.3: DNA (Marker) Tests for Canine Inherited Diseases 199
Table 7.4: U.S. Companion Animal Prescription Drug Revenue, 2006 202
Table 7.5: Companies Producing Generic Pharmaceuticals for Animal Health 203
Table 7.6: Generics vs. Branded Animal Health Pharmaceuticals, 2005 204
Table 7.7: U.S. Animal Health Generic Pharmaceuticals in the Pipeline, 2007 206
Table 7.8: Veterinary Pet Insurance Rates and Coverage in the U.S., 2008 209
Table 8.1: Pfizer Animal Health Products 250
Table 8.2: Pfizer Products Patents 252
Table 8.3: Key Pfizer Animal Health Products 254
Table 8.4: Pfizer Livestock Products 254
Table 8.5: Pfizer Equine Products 255
Table 8.6: Pfizer Companion Animal Products 255
Table 9.1: European Animal Health Market Sales, 2005-2012 266
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