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U.S. High Content Screening Markets
Frost & Sullivan, June 2007, Pages: 95


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The Frost & Sullivan research service titled U.S. High Content Screening Markets provides a market overview with estimates and forecasts of revenues, and share analysis, along with a complete analysis of key market drivers, restraints, challenges, strategies, and trends that are impacting the market. In this research, Frost & Sullivan's expert analysts thoroughly examine the high content screening instrumentation market and high content screening reagents and assays market.

Consolidation and Competition leading to Greater Market Concentration

The U.S. high content screening markets have witnessed considerable growth in the last ten years and as of early 2007, the markets were already in the development stages of their market life cycle. Accordingly, these markets have undergone substantial consolidation, leading to a high degree of competition as well as increasing price sensitivity, and decreasing technical change. While there are still approximately 50 companies that participate in the U.S. high content screening market, ongoing consolidation and competition have resulted in greater market concentration. In 2006, continued consolidation and competition allowed the top three market competitors to control about 52.9 percent of the market.

Interestingly, since the markets for high content screening technologies are growing at faster rate than the markets for most life sciences research technologies, major market participants have strategically acquired and integrated niche suppliers of high content screening technologies to boost corporate growth. What is more, the leading market participants have generally had important product portfolio that are complementary with the high content screening workflow. 'Between 2003 and 2007, major market participants, such as ThermoFisher, PerkinElmer, and MDS Analytical Technologies have acquired niche suppliers of high content screening technologies,' notes the analyst of this research service. 'Acquisition such as these are, in turn, promoting cross-sales and cost-effective marketing.'

High Content Screening Instrumentation Generating Maximum Revenues

High content screening equipment are a vital segment of the U.S. high content screening markets – they accounted for around 65.9 percent of the total U.S. high content screening market’s revenues in 2006. Readers, in particular, saw significant uptake as numerous technological applications have enabled manufacturers to place the technology in numerous settings. Such technology applications include pre-lead screening for pharmaceuticals candidates, toxicity screening of dietary supplements and determination of mechanisms of toxicity, among others. By the end of 2010, however, the proportion of revenues driven by the sales of instrumentation and reagents and assays will be about the same at 50.6 and 44.1 percent, respectively.

In order to remain competitive in a consolidating market, high content screening market participants must have a detailed understanding of the biological questions that their customers are putting forth. Typically, high content screening applications are involved in several different stages of the discovery pipeline; target identification, target validation, assay development and screening, secondary screening, and so on. 'For each of these stages of the discovery pipeline, researchers might pose several different questions that relate to hepatotoxicity, genotoxicity, neurotoxicity, apoptosis/necrosis, cell cycle, oxidative stress, or other types of biological activity and roles of specific targets in cell function,' says the analyst. 'Instead of developing technology-centric high content screening technologies, market participants must identify the biology in play, and then match the appropriate technologies to the biological questions being asked by customers.'


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