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Molecular System Bioenergetics: Energy for Life
John Wiley and Sons Ltd, Sep 2007, Pages: 633
The book takes account of the shifting perspective in the study of cellular energetics, for the first time addressing energy metabolism on a systems biology level. It includes a brief review of classical bioenergetics, but its main focus is on recent approaches to study systems bioenergetics, both on the cellular and on the organ level. Novel concepts of metabolite channeling and of metabolons are introduced. A large part is devoted to metabolic signaling and its pathological implications, e. g. in the so-called metabolic syndrome. The final part of the book describes the application of systems bioenergetics to the study of cancer, cell death and other medically important processes.
In this first integrated view, practically each of the world's leading experts has contributed to this one and only authoritative resource on the topic. Bringing systems biology to cellular energetics, they address in detail such novel concepts as metabolite channeling and medical aspects of metabolic syndrome and cancer.
About the author:
Valdur Saks is Professor of Bioenergetics and Biochemistry at the University of Grenoble, France, and Head of the Laboratory of Bioenergetics at the National Institute of Chemical and Biological Physics in Tallinn, Estonia. A graduate of Moscow University, he was the long-time head of the Laboratory of Cardiac Bioenergetics in Moscow, Russia, before taking up his present positions. Professor Saks has authored over 220 scientific publications and has received numerous scientific awards, including the USSR State Prize in Science and the Internatinoal 'Research and Development' Award sponsored by the U.N. and UNICEF. He is a member of the International Society for Heart Research and of the American Physiological and Biophysical Societies.
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