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Molecules and Medicine
John Wiley and Sons Ltd, Sep 2007, Pages: 272


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With focus on the most important and commonly used medicines such as anti-clotting agents, antibiotics, Viagra and anti-malarial and antidepressant drugs, coverage includes the condition it treats, the summary of its industrial development, the year put into practice, the biological target for the medicine, the human proteins related to the disease, the metabolism or action of the condition treated, and interacting side effects and related drugs. Diagrams revealing the shape and structure of molecular make-up for each medicine accompany the text. Interspersed where appropriate, can be found background sections such as a brief survey of immunology, to help guide the readers understanding.

This book is appropriate for a broad readership, starting with curious and thoughtful college undergraduates and reaching beyond to professors and researchers in the life sciences, chemistry, and medicine.  This book provides, for the first time ever, a completely integrated look at chemistry, biology, drug discovery, and medicine.

Molecules and Medicine delves into the discovery, application, and mode of action of more than one hundred of the most significant molecules now in use in modern medicine. Beautifully illustrated with full color throughout, molecule structures and shapes are shown for all of these medicines. The opening sections of the book provide a unique, clear, and concise introduction which enables the reader to understand chemical formulas.

For each medicine, coverage includes the condition it treats, the summary of its development in industry, the year put into practice, the biological target for the medicine, the human proteins related to the disease, the metabolism or action of the condition treated, and interacting side effects and related drugs.  Interspersed within the text, where appropriate, can be found background sections, such as a brief survey of immunology, to help guide the readers understanding.

About the authors:

E. J. Corey has been a Professor at Harvard University since 1959. He was educated at The Massachusetts Institute of Technology (1945-1950) and served as a faculty member at the University of Illinois from1951 to 1959. He is the 1990 Nobel Laureate in Chemistry, and the recipient of over seventy international awards and honorary degrees, including the U.S. National Medal of Science, the Japan Prize in Science, and the Priestley Medal of the American Chemical Society. He is amember of the U.S. National Academy of Sciences and the U.S. National Institute of Medicine. Professor Corey is the author of more than 1,000 publications and is one of the most cited authors in science.

Barbara Czakó completed undergraduate studies at the University of Debrecen, Hungary, where she worked with Dr. Sándor Berényi. She obtained a Master of Science degree at the University of Missouri-Columbia with Professor Shon R. Pulley. Dr. Czakó received her Ph.D. degree (2006) in synthetic organic chemistry under the guidance of Professor Gary A. Molander at the University of Pennsylvania. Currently she is a postdoctoral fellow with Professor E.J. Corey at Harvard University. In 2005 she published with László Kürti the textbook Strategic Applications of Named Reactions in Organic Synthesis.

László Kürti was born and raised in Hungary. He received his diploma from the University of Debrecen, Hungary, where he conducted research in the laboratory of Professor Sándor Antus. Subsequently he received his Master of Science degree at the University of Missouri-Columbia working with Professor Michael Harmata, and his Ph.D. degree (2006) in synthetic organic chemistry under the supervision of Professor Amos B. Smith III (the University of Pennsylvania). Currently he is a Damon Runyon Cancer Fellow in the group of Professor E.J. Corey at Harvard University. In 2005 he published with Barbara Czakó the textbook Strategic Applications of Named Reactions in Organic Synthesis.

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