|
|
 |
|
Viewing report
|
|
|
|
Nanotechnology: Revolutionizing R&D to Develop Smarter Therapeutics and Diagnostics
Business Insights, Jan 2008, Pages: 192
Nanotechnology: Revolutionizing R&D to develop smarter therapeutics and diagnostics
Executive summary
Nanotechnology: driving change in pharmaceutical R&D
Nanotechnology: drug research & development
Nanotechnology: nanoformulations & nanocarriers
Nanotechnology: diagnostics & imaging
Nanotechnology: therapeutic applications
Nanotechnology: regulations, patents and scientific publications
Nanotechnology: challenges, opportunities & future applications
Chapter 1 Driving change in pharmaceutical R&D
Summary
Defining nanotechnology
Nanotechnology funding
Nanotechnology evolution
Nanotechnology in the pharma industry
Nanotechnology start-up companies
Nanotechnology in academia
Drivers of nanotechnology research
Report Outline
Chapter 2 Drug research & development
Summary
Introduction
Nanotechnology in drug discovery & development
Nanotools for drug discovery & development
Application of nanotools in drug discovery & development
Nanoscaffolding
Nanoarrays
BioForce Nanosciences
Nanogen
Nanotubes & nanosensors
Nano-Proprietary Inc
Carbon Nanotechnologies Inc
Nanowires & cantilevers
Microfluidic lab-on-a-chip
Caliper Life Sciences
Nanofluidic lab-on-a-chip
Quantum Dots
Evident Technologies
Biomarker Harvesting
Instruments for nanodetection and analysis
Atomic force microscopy
Surface Plasmon Resonance
Instruments for nanofabrication
Dip Pen Nanolithography (DPN)
Conclusions
Chapter 3 Nanoformulations & nanocarriers
Summary
Introduction
Leading companies in nanoformulations
Approved nanoformulations
Dendrimers
Liposomal formulations
Pegylated liposomal formulations
Nanocrystal formulations
Nanoparticle formulations
Developmental nanoformulations
Protein-stabilized liposomal formulations
Controlled-release liposomal formulations
New controlled-release nanoparticle and nanosphere formulations
Magnetic nanoparticle formulations
Novel nanomaterials for drug delivery
Nanobombs
Nanoshells
Nanotubes
Conclusions
Chapter 4 Diagnostics & imaging
Summary
Introduction
Nanoarrays
Cystalline nanoarrays
Nanodevices
Magnetic nanoparticles, nanocapsules and nanocells
Nanoparticle barcodes
Multifunctional nanoparticles and nanocells
Gold nanoparticles
Fluorescent nanoparticles
Fluorescent nanocrystals
Nanoscale contrast agents
Multiplex imaging agents/therapeutics
Conclusions
Chapter 5 Therapeutic applications
Summary
Introduction
Nanotechnology in cancer
Research
In Vivo imaging
Molecular imaging & diagnostics
Drug delivery
Cancer conclusions
Nanotechnology in cardiovascular disease
Therapeutic research
Molecular imaging & diagnostics
Tissue engineering & regenerative medicines
Medical devices
Drug delivery
Cardiovascular conclusions
Nanotechnology in CNS
Research & development
Diagnostics & imaging
Drug delivery
Neurodevices and nanowires
CNS conclusions
Overall conclusions
Chapter 6 Regulations, patents and scientific
publications
Summary
Nanotechnology Guidelines
Patentability and publications
Nanotechnology patents
Nanotechnology-based publications
Conclusions
Chapter 7 Challenges, opportunities and future
applications
Summary
Introduction
Challenges in adopting nanotechnology
Regulations
Legal, political and ethical issues
Public perception of nanotechnology
Multidisciplinary infrastructure
Intellectual property
Commerciality of existing nanotechnology and medicines
Opportunities for adopting nanotechnology
Product repositioning
New imaging agents for early disease detection
Point-of-care diagnostics
Personalized medicines
Implementing nanotechnology in the pharma industry
Competitive strategies
AstraZeneca
Bristol-Myers Squibb
GlaxoSmithKline
Novartis
Roche
Pfizer
Elan Corporation
Genentech
GE Healthcare
Siemens Medical Solutions
Abraxis BioSciences
pSividia Limited
StarPharma Holdings Ltd
Alliances & licensing
Future impact of nanotechnology on drug discovery & development
Chapter 8 Appendix
Glossary
Bibliography
Index
Endnotes
List of Figures
Figure 1.1: Nanometer scale
Figure 1.2: Top-down and bottom-up nanotechnology approach
Figure 1.3: Applications of nanotechnology
Figure 1.4: Global nanotechnology funding, 2003
Figure 1.5: Global nanotechnology market by 2015
Figure 1.6: Evolution of nanotechnology 2000-2020
Figure 1.7: Evolution of the nanotechnology market
Figure 1.8: Nanotechnology applications in the pharma industry
Figure 2.9: Nanotechnology innovating the R&D process
Figure 2.10: Applications of nanotechnologies in drug discovery & development
Figure 2.11: TEM of native collagen fibers and nanoscaffolding
Figure 2.12: Array of probes on nanoarray
Figure 2.13: Bead Nanoarrays from NanoVic
Figure 2.14: NanoChip® 400 System
Figure 2.15: Nanosensors for analyte detection
Figure 2.16: Nanowires and cantilevers for nanodetection and multiplexing
Figure 2.17: Scanning electron microscope image of a five-nozzle M3 emitter
Figure 2.18: Evolution of microfluidics and nanofluidics in the pharma industry
Figure 2.19: Nanoparticle bioconjugate harvesting platform
Figure 2.20: Schematic of ATM technology
Figure 2.21: AFM images measuring real-time cell activity
Figure 2.22: Schematic of SPR technology
Figure 2.23: Schematic of DPN technology and its applications
Figure 3.24: Nanoformulations driving drug delivery
Figure 3.25: Dendrimer structure
Figure 3.26: Dendrimer delivery platform
Figure 3.27: DauxoXome® liposomal formulation
Figure 3.28: Doxil® liposomal formulation versus non-liposomal formulation
Figure 3.29: Enhanced bioavailability and absorption rate with Nanocrystals technology
Figure 3.30: Abraxane nab technology - Photosphere
Figure 3.31: Micellar nanoparticles (MNP)
Figure 3.32: Controlled-release liposomal formulations
Figure 3.33: Fullerene structures A) C-60 and B) C-70
Figure 3.34: AuroLase™ treated mice versus sham treatment
Figure 3.35: Carbon nanotubes
Figure 4.36: Nanotechnologies advancing diagnostics and imaging
Figure 4.37: ViriChip™ Virus Detection Platform
Figure 4.38: S-layer technology platform
Figure 4.39: Sensation™ Virus Detection Platform
Figure 4.40: BioNanoChannel ™ Bacterial Detection Platform
Figure 4.41: Biobarcode assays for the detection of PSA
Figure 4.42: Biosensor biobarcode
Figure 4.43: Oxonica’s Nanoplex™ biotag and POC diagnostic
Figure 4.44: AuroVist™ microCT image
Figure 4.45: NanoStrings™ Nanoparticle Barcoding
Figure 4.46: Schematic of fluorescent A) lanthanide structure and B) lanthanide nanoparticles
Figure 4.47: QDot Nanocrystal Structure
Figure 4.48: TriLite™ Emission Spectra
Figure 4.49: Viral Capsids as imaging carriers
Figure 4.50: Multifunctional nanocarriers for detection, diagnosis and treatment
Figure 4.51: Nanotechnology improving molecular detection and diagnosis of cancer
Figure 5.52: Application of nanotechnology in cancer, cardiovascular and CNS disorders
Figure 5.53: Cyberkinetic’s brain gate
Figure 6.54: Federal regulators addressing different aspects of nanotechnology
Figure 6.55: Japanese Governmental System for Science & Technology
Figure 6.56: Worldwide nanopatents 1995-2003
Figure 6.57: Worldwide nanopatents by region of applicant and inventor
Figure 6.58: Worldwide nanoscientific publications per world region
Figure 6.59: Worldwide nanoscientific publications per country and subfield 1999-2004
Figure 7.60: Future impact of nanotools on pharmaceuticals and healthcare
Figure 7.61: Health care trends to 2020 - GlaxoSmithKline 1
List of Tables
Table 1.1: Leading nanotechnology start-up companies
Table 1.2: Leading nanotechnology institutes, forums and networking organizations
Table 2.3: Key attributes of PuraMatrix versus other ECMs
Table 2.4: Leading Lab-on-Chip (LOC) and microfluidic manufacturers
Table 2.5: Leading manufacturers of QDots
Table 2.6: Advantages of DPN versus other top-down and bottom-up fabrication technologies
Table 3.7: Approved nanoformulations
Table 3.8: Leading nanoformulation companies
Table 4.9: Leading diagnostics and imaging companies evaluating nanotechnology
Table 5.10: Nano-enabled delivery system for cancer therapeutics
Table 5.11: Approved & developmental cancer nanomedicines
Table 5.12: Nanotechnology application in cardiovascular devices
Table 5.13: Nano-enabled delivery system under evaluation for cardiovascular therapies
Table 5.14: Nano-enabled delivery system under evaluation for CNS therapies
Table 7.15: Recent alliances and licensing deals in nanotechnology
Product samples
A sample for this product is available. Please Login/Register to download this sample.
Customers who bought this item also bought
Global Market and Applications for Nanotechnology in the Life Sciences and Healthcare Industries
Bio Nanotechnology
The Nanotechnology Opportunity Report (NOR) 2008, 3rd Edition
Nanotechnology in Europe 2009
Biomedical Applications of Nanotechnology
Nanotechnology - Global Outlook
Nanotechnology for Drug Discovery and Drug Design
The World Nanotechnology Market (2006)
Nanotechnology Market Forecast to 2011
Nanoparticle Drug Delivery Market Report
The Role of Nanotechnology in European Drug Discovery
Nanotechnology Industry Impact Research Service
|
|
|
|
