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Pipeline and Commercial Insight: Schizophrenia - Second Generation Depots Protect Market Value
Datamonitor, Oct 2008, Pages: 277


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Schizophrenia is a chronic and severe mental health disorder affecting around 4.6 million schizophrenia sufferers across the seven major markets. Currently led by oral branded atypical antipsychotics, the schizophrenia market will undergo some big changes over the period 20082017. Prospective players can expect to face stiff competition from generic versions of all currently branded drugs.

Scope

- Analysis of key marketed brands and late-stage pipeline drugs.

- Schizophrenia-specific drug sales volume and value forecasts to 2017 in the US, Japan, and five major European markets.

- Identification of future market events that are expected to affect schizophrenia drug revenues.

- Analysis of patient potential, unmet needs and clinical trial design in schizophrenia.

Highlights of this title

The schizophrenia market is anticipated to grow slowly until 2011 to reach $4.3 billion across the 7MM. Despite the launch of a few pipeline drugs, the market will decline thereafter owing to the widespread launch of generic risperidone by the end of 2008, followed by generic versions of all currently marketed schizophrenia drugs from 2011 onwards.

The increasing uptake of long-acting injectable (depot) atypical antipsychotics is expected to partially alleviate the branded schizophrenia sales decline. Positive effects on patient compliance will stimulate sales of these formulations which are forecast to reach a combined value of $1.2 billion by 2013.

The schizophrenia late-stage pipeline lacks innovation. Sales of most oral investigational drugs will be limited by extensive generic competition across the 7MM. However, drugs with novel mechanism of action could prove commercially successful, demanding a price premium and offering alternative treatments for refractory patients.

Key reasons to purchase this title

- Understand the current schizophrenia market dynamics and how they are expected to evolve out to 2017.

- Benchmark key late-stage pipeline schizophrenia compounds against the current market leading brands.

- Understand unmet needs and opportunities in the schizophrenia market based on key opinion leader comments.



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