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Drug Delivery Technology - Revolutionizing Cardiovascular Treatment
PharmaVision, July 2007, Pages: 109


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“The ability to deliver therapeutics site specifically,safely and efficiently remains a major challenge for the treatment of cardiovascular diseases. Additional drug delivery hurdles will need to be overcome as pharma companies and medical device manufacturers target specific areas of the vasculature. These advances will help to develop a new generation of medicines and devices to tackle the world’s leading killer.” Dr Cheryl Barton

Cardiovascular disease (CVD) is the leading cause of death in the world, killing almost 17 million people each year. Types of CVD include coronary heart disease, hypertension, dyslipidemia and stroke - stroke is now the third leading cause of death, and the leading cause of disability in the western world (source: American Heart Association, AHA). Each year these conditions account for almost half of all deaths and are a tremendous financial burden on the healthcare system estimated to cost the US around US$560 billion annually (Source: Buxton, 2007).

The following report summarizes some of the latest developments in CV drug development and devices and analyzes some of the most promising solutions which drug delivery companies and device manufacturers are providing in order to address this unmet clinical need.

Use the incisive analysis, commentary, opinions and forecasts provided in this note to:

-gain an in-depth understanding of the technology landscape for CV devices including active & passive targeting platforms, cell- & genebased
therapeutic delivery platforms & biomaterials for medical devices including drug-eluting stents

-assess the options available for delivering existing & novel cardiovascular agents now & in the future

-gauge the current & future technology requirements of pharma, biotech & medical device companies developing cardiovascular products & devices

-analyze how the market is evolving & the influence that drug delivery may have on pharma cardiovascular pipelines

-identify key pharma & delivery companies focusing on the improved delivery of existing & novel cardiovascular agents

-highlight alliances between delivery companies & pharma & device manufacturers and recent market activity

-evaluate where progress has been made in the delivery of potential new cardiovascular products & devices

Eight Questions this Note Answers:

1. How will the drug delivery technology drivers change in the cardiovascular arena during the next decade and beyond?

2. What are the key delivery technologies and devices in the cardiovascular field?

3. When are products and medical devices which utilize these key delivery technologies likely to reach the market?

4. Which drug delivery specialists are forming strategic alliances with the pharma industry in the cardiovascular arena?

5. Which companies are the winners in each technology category?

6. How are drug delivery technologies evolving to meet the demands of the cardiovascular market?

7. Where are the market opportunities now and in the future?

8. What do we predict will be the value of the cardiovascular drug delivery and medical devices market each year until 2012, in 2015 and in 2020?

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