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Cell Signal Inhibitors: A New Generation of Prophylactic Agents
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Description: |
In view of the role of Cox-2 not only in colon cancer, but also in other major tumor indications, Cox-2 inhibitors have the potential to revolutionize cancermanagement, should their reported efficacy against colon polyp recurrencetranslate into a survival advantage. |
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Contents: |
TABLE OF CONTENTS
EXECUTIVE SUMMARY
COX-2 inhibitors
Introduction
Cell signaling
Cell signaling in cancer
The targets of cell signal inhibitors
Tyrosine kinases
Lipid signaling
COX-2
The future market for cell signal inhibitors
Unmet needs
Can cell signal inhibitors fill the gaps?
Pipeline analysis
Pipeline overview
Iressa
Glivec (STI 571)
IMC-C225
OSI-774
CEP-701
ISIS 3521
ISIS 5132
ISIS 2503
R115777
Celebrex (Celecoxib)
Vioxx (Refocoxib)
Apra
P54
Competitive Analysis
Forecasts for cell signal inhibitors
Forecast launches
Market size for cell signal inhibitors in 2007
CONCLUSIONS AND SUMMARY
References
APPENDIX
Introduction to Datamonitor
About Healthcare
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