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Acute Myeloid Leukemia: Cytarabine Here to Stay
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Description: |
Acute Myeloid Leukemia (AML) is an aggressive form of leukemia, mainly affecting the adult population, and within this subset, affecting males more than females. Approximately 23,000 individuals are expected to be diagnosed with AML over next year in the US, Japan and Europe. The likelihood of survival of AML patients is most easily defined by the genotype initiating the disease. The prognosis defined in this way can range from very poor to extended disease free survival in the most treatable cases. This brief provides an overview of the AML market, exploring the epidemiology and the most widely used treatment approaches. Subsequent sections of the brief examine the predicted evolution of the AML market with the release of some long awaited drugs and the future perspectives of the drug market. |
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Contents: |
TABLE OF CONTENTS
EXECUTIVE SUMMARY
Disease overview
Acute Myeloid Leukemia
Epidemiology
Risk factors
DIAGNOSIS AND TREATMENT OF AML
Diagnosis and Staging
Treatment of AML
Overview
Stage specific breakdown of treatment
Remission therapy for AML
Currently approved drugs
Cytarabine
Daunorubicin
Idamycin (idarubicin)
Cost of AML treatment
UNMET NEEDS IN AML
AML PIPELINE
Gleevac (STI 571)
Proleukin (Aldesleukin)
Ceplene (Histamine dihydrochloride)
SMART HuM195
Troxatyl (troxacitabine)
Annamycin
DX-8951f
Irofulven
Others
Future incidence of AML
Trends in the cancer market to 2007
The niche cancer market
Market forecast for AML pipeline
References
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