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Acute Myeloid Leukemia: Cytarabine Here to Stay


Description: Acute Myeloid Leukemia (AML) is an aggressive form of leukemia, mainly affecting the adult population, and within this subset, affecting males more than females. Approximately 23,000 individuals are expected to be diagnosed with AML over next year in the US, Japan and Europe. The likelihood of survival of AML patients is most easily defined by the genotype initiating the disease. The prognosis defined in this way can range from very poor to extended disease free survival in the most treatable cases. This brief provides an overview of the AML market, exploring the epidemiology and the most widely used treatment approaches. Subsequent sections of the brief examine the predicted evolution of the AML market with the release of some long awaited drugs and the future perspectives of the drug market.


Contents:
TABLE OF CONTENTS


EXECUTIVE SUMMARY


Disease overview


Acute Myeloid Leukemia


Epidemiology


Risk factors


DIAGNOSIS AND TREATMENT OF AML


Diagnosis and Staging



Treatment of AML


Overview


Stage specific breakdown of treatment


Remission therapy for AML


Currently approved drugs


Cytarabine


Daunorubicin


Idamycin (idarubicin)


Cost of AML treatment



UNMET NEEDS IN AML




AML PIPELINE



Gleevac (STI 571)


Proleukin (Aldesleukin)


Ceplene (Histamine dihydrochloride)


SMART HuM195


Troxatyl (troxacitabine)


Annamycin


DX-8951f


Irofulven


Others


Future incidence of AML


Trends in the cancer market to 2007


The niche cancer market



Market forecast for AML pipeline


References













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Please fax this form to:
(646) 607-1907 or (646) 964-6609 - From USA
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