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Brain metastases


Description: Though many drugs have been shown to have activity in brain metastases, none are commonly used. Accordingly, pharmaceutical management of brain metastases is an area with great unmet need and little competition. This Market Brief examines the epidemiology, diagnosis and treatment of brain metatases, highlights unmet needs in treatment, and provides an examination of drugs in the pipeline and as well as drugs currently indicated for other cancer types.


Contents:
TABLE OF CONTENTS


EXECUTIVE SUMMARY


INTRODUCTION


Disease overview


Epidemiology



DIAGNOSIS AND TREATMENT OF BRAIN METASTASES



Diagnosis and Staging


Characteristics of metastatic brain tumors


Staging and Prognosis


Treatment of brain metastases


Overview


Country-level treatment of brain metastases


SURGERY


WHOLE BRAIN RADIOTHERAPY


RADIOSURGERY


DRUG THERAPY



UNMET NEEDS, TRENDS AND RECOMMENDATIONS




BRAIN METASTASES PIPELINE



Drugs approved in other indications


Temodar/Temodal (temozolomide)


Drugs in development


RSR13


Xcyrtin


Xerecept


APPENDIX


References



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