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Cardiac Markers - Making their Mark on the Medicines Market


Description: This brief sets out to: * Review the available diagnostic markers for cardiac ischemia, atherosclerotic disease, heart failure, and platelet function. The four classes of cardiac markers are presented in order of their respective market size, with ischemia markers representing the largest market, and markers of platelet function the smallest. * Analyze each class of marker with respect to accuracy, convenience, usefulness, cost, and inherent shortcomings and/or limitations, and provide a rating for each class based on these parameters * consider the commercial implications of each class of cardiac marker, including the likely impact(s) on the existing CV diagnostics and therapeutics markets * discuss the future role of genetic analysis in shaping the diagnostics and therapeutics markets, with attention paid to genetic markers currently under investigation.


Contents:
EXECUTIVE SUMMARY






Introduction


Methodology for assessment of cardiac markers


Markers of acute cardiac ischemia


Introduction


A host of currently available markers


Cardiac-specific troponins


Implications of cardiac troponins on the CV therapeutics market


Available troponin tests


Markers for long-term CAD risk stratification


C-reactive protein (CRP)


Homocysteine


Markers of heart failure


Brain natriuretic peptide (BNP)


Markers of platelet activation


Introduction/background


Clinical trials using platelet function testing


Impact on CV therapeutics market


Currently available testing devices






Genetic markers


Appendix







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Cardiac Markers - Making their Mark on the Medicines Market

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Please fax this form to:
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