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Cardiac Markers - Making their Mark on the Medicines Market
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Description: |
This brief sets out to: * Review the available diagnostic markers for cardiac ischemia, atherosclerotic disease, heart failure, and platelet function. The four classes of cardiac markers are presented in order of their respective market size, with ischemia markers representing the largest market, and markers of platelet function the smallest. * Analyze each class of marker with respect to accuracy, convenience, usefulness, cost, and inherent shortcomings and/or limitations, and provide a rating for each class based on these parameters * consider the commercial implications of each class of cardiac marker, including the likely impact(s) on the existing CV diagnostics and therapeutics markets * discuss the future role of genetic analysis in shaping the diagnostics and therapeutics markets, with attention paid to genetic markers currently under investigation. |
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Contents: |
EXECUTIVE SUMMARY
Introduction
Methodology for assessment of cardiac markers
Markers of acute cardiac ischemia
Introduction
A host of currently available markers
Cardiac-specific troponins
Implications of cardiac troponins on the CV therapeutics market
Available troponin tests
Markers for long-term CAD risk stratification
C-reactive protein (CRP)
Homocysteine
Markers of heart failure
Brain natriuretic peptide (BNP)
Markers of platelet activation
Introduction/background
Clinical trials using platelet function testing
Impact on CV therapeutics market
Currently available testing devices
Genetic markers
Appendix
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Cardiac Markers - Making their Mark on the Medicines Market
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