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MicroRNA Profiling in Cancer: A Bioinformatics Perspective

Pan Stanford Publishing Pte. Ltd., Sep 2009, Pages: 300


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The recent discovery of microRNAs - a new class of non-coding RNAs - has revolutionized modern biomedical sciences. This book presents current advances in the emerging interdisciplinary field of microRNA research of human cancers from a unique perspective of quantitative sciences: bioinformatics, computational and systems biology and mathematical modelling.

This volume contains adaptations and critical reviews of the recent state-of-the-art studies, ranging from technological advances in microRNA detection and profiling, clinically oriented microRNA profiling in several human cancers, to a systems biology analysis of global patterns of microRNA regulation of signalling and metabolic pathways. Interactions with transcription factor regulatory networks and mathematical modelling of miRNA regulation are also discussed.

Readership: A broad audience of academic, and biotech and pharmaceutical industry biomedical scientists, physicians involved in cancer research, oncologists, computational biologists, and bioinformaticians who are involved in basic, translational and clinical research as well as college educators, undergraduate and graduate and medical students.

Edited by Yuriy Gusev (University of Oklahoma, USA)



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