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Apoptotic Therapeutics in Oncology - Where to Commercialize?

Bioseeker, Nov 2009, Pages: 803


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The report is written for you to understand and assess the impact of competitor entry and corresponding changes to development strategies for your own portfolio products. It serves as an external commercial advocate for pharmaceutical companies’ portfolio planning and new product planning.

This report comprises defined and up to date development strategies for 171 apoptotic drugs (519 projects) within the portfolio of 125 investigators, from Ceased to Pre-registration. The report extensively analyses 146 identified targets of apoptotic drugs, organized into 120 drug target profiles, and assesses them in 53 different cancer indications.

The report is written for you to understand and assess the impact of competitor entry and corresponding changes to development strategies for your own portfolio products. It serves as an external commercial advocate for pharmaceutical companies’ portfolio planning and new product planning by:

Providing you with competitive input to the R&D organization to guide development of early product ideas and ensure efforts are aligned with business objectives

Assisting you to make informed decisions in selecting cancer indications that are known to be appropriate for your drug's properties

Analyzing, correlating and integrating valuable data sources in order to provide accurate data for valuation of pipeline, in-licensing and new business opportunities

Providing you with commercial analytic support for due diligence on in-licensing and acquisition opportunities

Integrating knowledge for you to consider the therapeutic target for the highest therapeutic outcome and return on investment

This report will also be an important part of creating and implementing a market development plan for any apoptotic drug in oncology to ensure that the optimal market conditions exist by the time the product is commercialized.

This report includes 171 apoptotic drugs in oncology. From Ceased to Pre-registration ones.

A shortlist of drugs included are:
- 2-methoxyestradiol
- ABT-263
- AEG-35156
- afutuzumab
- alvocidib
- Apomab
- ARQ-197
- AS-1411
- atiprimod dimaleate
- ATN-224
- belinostat
- BZL-101
- canfosfamide hydrochloride
- CBLC-102
- cenersen
- cintredekin besudotox
- combretastatin A-4 prodrug
- conatumumab
- CS-1008
- dulanermin
- GCS-100LE
- GRN-163L
- HE-3235
- idronoxil
- indisulam
- INGN-241
- INGN-401
- ISIS-23722
- kahalalide F
- lonaprisan
- lumiliximab
- mapatumumab
- MGCD-0103
- MKC-1
- motexafin gadolinium
- oblimersen sodium
- panobinostat
- PARP inhibitors
- PAT-SC1
- patupilone
- PCI-24781
- plitidepsin
- quarfloxacin
- retaspimycin
- Rh-Apo2L
- sagopilone
- seliciclib
- tigapotide triflutate
- TLN-232
- triciribine
- TRU-016
- voreloxin
- VX-944
- XL-647


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