Contents:

Executive summary Market overview Market dynamics Global DNA sequencing tools & services market Company profiles Chapter 1 Market overview Summary Evolution of DNA sequencing DNA sequencing and drug discovery Defining the market Need for more reliable and compatible tools High throughput and next-generation sequencing – attractive growth factors DNA sequencing tools dominate the market Protecting DNA sequencing technology Applications of DNA sequencing Drug development Clinical trials Whole genome testing Toxicology prediction Identification of drug resistance Drug discovery Chapter 2 Market dynamics Summary Introduction Regional markets North America Europe Asia RoW Competitive landscape Recent agreements and collaborations Recent launches Market drivers Funding from public institutes NGS technologies Patient profiling for genetic disorders Development of personalized medicine High productivity rates Market restraints Shift in sequencing market trends Introduction of NGS technologies Chapter 3 Global DNA sequencing tools & services market Summary DNA sequencing tools Microarray Biochip microarray Gel array Array design kit Low and high density microarrays Bioinformatics Electrophoresis Gel electrophoresis Capillary electrophoresis DNA sequencing kits Consumables, chemicals, reagents and probes DNA polymerase Primers Automated DNA sequencers Chromatography DNA amplification (PCR) Mass spectrometry Microscopy-based techniques Electron microscopy Atomic force microscopy Microfluidics-enabled workstations Barcode readers for DNA sample presentation Computational chemistry and biology modeling Spotters/arrayers Centrifuge Scanners Thermal cyclers Charge-coupled devices (CCDs) Plates, strips and columns DNA sequencing services High throughput sequencing Shotgun sequencing Re-sequencing Sample process and primer walking Single pass analysis Bacterial identification Market drivers Microarray technology is a powerful tool for high throughput screening Increasing applications of microarrays Increasing applications of bioinformatics in R&D Technological breakthroughs generate need for efficient DNA sequencing Genomics and drug discovery applications of automated sequencers Diagnostic applications of automated sequencers Applications in comparative research projects of automated sequencers Developments in PCR technology PCR is a reliable tool for multiple applications Government initiative for funding Market restraints Limited scope of microarrays for pathogen enumeration Time loss due to large number of laboratory specific variations for microarrays Low cost next-generation technologies hinder growth of microarrays Incompatibility issues of current bioinformatics tools High cost of modifying supporting products High cost and reliability issues of PCR technology Chapter 4 Company profiles Summary 454 Life Sciences Company overview Products and services Company strategy Other events Affymetrix Company overview Product and services Company strategy Agilent Technologies Company overview Products and services Company strategy Beckman Coulter, Inc Company overview Products and services Company strategy Bio-Rad Laboratories Company overview Products and services Company strategy Caliper Life Sciences Company overview Products and services Company strategy CapitalBio Corp Company overview Products and services Company strategy CombiMatrix Corp Company overview Products and services Company strategy Commonwealth Biotechnologies, Inc Company overview Products and services Company strategy Complete Genomics, Inc Company overview Products and services Company strategy DNA Vision Company overview Products and services Company strategy Enzo Biochem, Inc Company overview Products and services Company strategy EPICENTRE Biotechnologies Company overview Products and services Company strategy Eurofins MWG Operon Company overview Products and services Company strategy GE Healthcare Company overview Products and services Company strategy Gen-Probe Life Sciences Company overview Products and services Company strategy GVK Biosciences (GVK BIO) Company overview Products and services Company strategy Helicos BioSciences Corp Company overview Products and services Company strategy Illumina, Inc Company overview Products and services Company strategy Integrated DNA Technologies Company overview Products and services Company strategy Kapa Biosystems, Inc Company overview Products and services Company strategy Life Technologies Corp Company overview Products and services Company strategy Microchip Biotechnologies, Inc Company overview Products and services Company strategy Nanogen, Inc Company overview Products and services Company strategy Ocimum Biosolutions Ltd Company overview Products and services Company strategy Pacific Biosciences Company overview Company strategy PamGene Company overview Products and services Company strategy Promega Corp Company overview Products and services Company strategy QIAGEN Company overview Products and services Company strategy Sequenom Company overview Products and services Company strategy Shimadzu Biotech Company overview Products and services Company strategy Siemens Healthcare Diagnostics Company overview Products and services Company strategy Sigma-Aldrich Company overview Products and services Company strategy SoftGenetics, LLC Company overview Products and services Company strategy Thermo Fisher Scientific, Inc Company overview Products and services Company strategy Third Wave Technologies, Inc Company overview Products and services Company strategy VisiGen Biotechnologies Company overview Products and services Company strategy ZS Genetics Company overview Products and services Company strategy Chapter 5 Appendix Glossary Patents List of Figures: Figure 1.1: Developments in DNA sequencing Figure 1.2: DNA sequencing in drug discovery and development Figure 1.3: DNA sequencing and drug discovery market Figure 1.4: Relative importance of features of DNA sequencing tools, 2009 versus 2014 Figure 1.5: DNA sequencing market drivers Figure 1.6: DNA sequencing tools market dynamics Figure 1.7: Patent analysis by technology, 2007 versus 2009 Figure 1.8: Patent analysis by geography, 2006 versus 2008 Figure 1.9: Patent applications (%) by competitors, 2004– Oct 09 Figure 2.10: Major segments of the global DNA sequencing market (%), 2008–09 Figure 2.11: Competitive landscape (%), 2008–09 List of Tables: Table 1.1: Global DNA sequencing market by tools and services ($m), 2007–14 Table 1.2: Global DNA sequencing applications market by applications ($m), 2007–14 Table 1.3: Global drug development market, by applications ($m), 2007–14 Table 1.4: Global drug discovery market, by applications ($m), 2007–14 Table 2.5: Global DNA sequencing market, by geography ($m), 2007–14 Table 2.6: Agreements and collaborations in the DNA sequencing market, 2008–09 Table 2.7: New product, technology & service launch in the DNA sequencing market, 2008–09 Table 2.8: New product, technology & service launch in the DNA sequencing market, 2008–09 (ctd1) Table 2.9: New product, technology & service launch in the DNA sequencing market, 2008–09 (ctd2) Table 2.10: New product, technology & service launch in the DNA sequencing market, 2008–09 (ctd3) Table 3.11: Global DNA sequencing tools market, by geography ($m), 2007–14 Table 3.12: Global DNA sequencing tools market, by products ($m), 2007–14 Table 3.13: Global microarray market, by products ($m), 2007–14 Table 3.14: Global microarray market, by geography ($m), 2007–14 Table 3.15: Global biochip microarray market, by geography ($m), 2007–14 Table 3.16: Global gel array market, by geography ($m), 2007–14 Table 3.17: Global array design kit market, by geography ($m), 2007–14 Table 3.18: Global high and low density microarray market, by geography ($m), 2007–14 Table 3.19: Global bioinformatics market, by products ($m), 2007–14 Table 3.20: Global bioinformatics market, by geography ($m), 2007–14 Table 3.21: Global electrophoresis market, by products ($m), 2007–14 Table 3.22: Global electrophoresis market, by geography ($m), 2007–14 Table 3.23: Global gel electrophoresis market, by geography ($m), 2007–14 Table 3.24: Global capillary electrophoresis market, by geography ($m), 2007–14 Table 3.25: Global DNA sequencing kits and others market, by geography ($m), 2007–14 Table 3.26: Global consumables, chemicals, reagents and probes market, by products ($m), 2007–14 Table 3.27: Global consumables, chemicals, reagents and probes market, by geography ($m), 2007– Table 3.28: Global DNA polymerase market, by geography ($m), 2007–14 Table 3.29: Global primers market, by geography ($m), 2007–14 Table 3.30: Global automated DNA sequencers market, by geography ($m), 2007–14 Table 3.31: Global chromatography market, by geography ($m), 2007–14 Table 3.32: Global DNA amplification (PCR) market, by geography ($m), 2007–14 Table 3.33: Global mass spectrometry market, by geography ($m), 2007–14 Table 3.34: Global microscopy-based techniques market, by products ($m), 2007–14 Table 3.35: Global microscopy-based techniques market, by geography, ($m), 2007–14 Table 3.36: Global electron microscopy market, by geography ($m), 2007–14 Table 3.37: Global AFM market, by geography ($m), 2007–14 Table 3.38: Global microfluidics-enabled workstations market, by geography ($m), 2007–14 Table 3.39: Global barcode readers market for DNA sample presentation, by geography ($m), 2007– Table 3.40: Global computational chemistry and biology modeling market, by geography ($m), 2007– Table 3.41: Global spotters/arrayers market, by geography ($m), 2007–14 Table 3.42: Global centrifuge market, by geography ($m), 2007–14 Table 3.43: Global scanners market, by geography ($m), 2007–14 Table 3.44: Global thermal cycler market, by geography ($m), 2007–14 Table 3.45: Global charge-coupled devices market, by geography ($m), 2007–14 Table 3.46: Global plates, strips and columns market by geography ($m), 2007–14 Table 3.47: Global DNA sequencing services market by products ($m), 2007–14 Table 3.48: Global DNA sequencing services market, by geography ($m), 2007–14 Table 3.49: Global high throughput sequencing market, by geography ($m), 2007–14 Table 3.50: Global shotgun sequencing market, by geography ($m), 2007–14 Table 3.51: Global re-sequencing market, by geography ($m), 2007–14 Table 3.52: Global sample process and primer walking market by geography ($m), 2007–14 Table 3.53: Global single pass analysis market, by geography ($m), 2007–14 Table 3.54: Global bacterial identification market, by geography ($m), 2007–14 Table 5.55: US patents Table 5.56: US patents (ctd 1) Table 5.57: US patents (ctd 2) Table 5.58: US patents (ctd 3) Table 5.59: US patents (ctd 4) Table 5.60: US patents (ctd 5) Table 5.61: US patents (ctd 6) Table 5.62: US patents (ctd 7) Table 5.63: US patents (ctd 8) Table 5.64: European patents Table 5.65: European patents (ctd 1) Table 5.66: European patents (ctd 2) Table 5.67: European patents (ctd 3) Table 5.68: European patents (ctd 4) Table 5.69: European patents (ctd 5) Table 5.70: European patents (ctd 6) Table 5.71: European patents (ctd 7) Table 5.72: European patents (ctd 7) Table 5.73: European patents (ctd 8) Table 5.74: European patents (ctd 9) Table 5.75: European patents (ctd 10) Table 5.76: European patents (ctd 11) Table 5.77: Japanese patents Table 5.78: Japanese patents (ctd 2) Table 5.79: Japanese patents (ctd 3) Table 5.80: Japanese patents (ctd 4)

Companies Mentioned

- 454 Life Sciences - Affymetrix - Agilent Technologies - Beckman Coulter, Inc. - Caliper Life Sciences - CombiMatrix Corp. - GE Healthcare - Helicos BioSciences Corp. - Illumina, Inc - Life Technologies Corp. - Nanogen Inc. - Ocimum Biosolutions Ltd. - Pacific Biosciences - PamGene - QIAGEN - Thermo Fisher Scientific Inc