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Aneurysm Flow Modulating Device Market Current Status & Strategic Opportunities


Description: With ev3 valuing Chestnut Medical Pipeline Embolization Device Technology at $150 million and forecasting a market of $350 million for cerebral flow diversion devices by 2013, the floodgates for innovation in the paradigm-shifting field of aneurysm flow modulation have just been blown away.

The unmet medical need is vast, from difficult to coil wide-necked cerebral aneurysms to hard-to-repair thoraco-abdominal aortic aneurysms, and the technology is proving itself to be safe, logical and accessible to small & medium size entrepreneurial start-ups.

Endovascular treatment of aneurysms has evolved substantially over the past two decades, transitioning from an investigational therapy into routine clinical practice and ultimately emerging as the treatment of choice for many lesions.

To date, endovascular therapy has been almost exclusively focused on filling the aneurysm sac with embolic material (coils or liquid embolics) or bridging the aneurysm with a covered stent (Stent Graft).

The idea behind the use of endovascular flow modulating (diverting) devices as monotherapy for endovascular aneurysm repair stems from the concept that a low porosity stent bridging the aneurysm neck modulates hemodynamic flow away from the vortex and streamlines blood flow within parent artery.

Dedicated flow diverting devices for eliminating cerebral aneurysms from circulation without the need for coils have already been cleared for marketing in Europe since mid-2008 and dedicated flow modulating devices for peripheral aneurysm repair entered the European market in 2009.

The market for aneurysm flow modulating devices is still in the embryonic stage with windows of opportunities opening for early entrants. Due to the novelty of the paradigm-shifting technology, little notice was taken of the market potential by large multinationals until ev3 adopted, and started publicizing the technology.

The hypothesis that wall shear stress modulates endothelial cellularity is gaining increasing support from researchers in the field. However, few companies are currently developing dedicated flow modulating devices with designs that take into consideration hemodynamic flow and endothelial growth dynamics.

Aneurysm Flow Modulating Device Market - Current Status & Strategic Opportunities is the first report to cover the market of flow-diverting devices for aneurysm reconstruction and repair.

The report is an exclusive introduction to this emerging market and provides a thorough, analysis of both the technology and markets with analysis of existing markets for cerebral, abdominal aortic, thoracic aortic and peripheral aneurysms, profiles of leading participants and forecasts to the year 2015.

With Aneurysm Flow Modulating Device Market - Current Status & Strategic Opportunities, you’ll be able to better:

- Assess market size and growth potential for aneurysm flow diverting devices.

- Identify emerging technologies and the companies behind them.

- Leverage your own technology and brainstorm new business opportunities.

- Understand current market dynamics, competitors’ positions and market shares.

- Assess market potential and have access to forecasts till 2015.

- Monitor the competition’s marketed and in-development products.

- Investigate mergers, acquisitions and licensing possibilities.

- Get a feel of the magnitude of the opportunity that fluid diverting devices presents and contemplate your company position towards this market transforming technology.

Aneurysm Flow Modulating Device Market - Current Status & Strategic Opportunities is targeted at senior executives in medical technology companies who are interested in developing an understanding of this emerging growth area.


Contents: 1. Executive Summary

2. Introduction & Overview

2.1 Definitions & Scope
2.2 Aortic Aneurysms
2.3 Cerebral (Intracranial) Aneurysms
2.4 Peripheral Artery Aneurysms


3. Aneurysm Flow Modulating Devices

3.1 Aneurysm Initiation, Progression & Rupture
3.2 Flow Modulation Concept for Aneurysm Repair
3.3 Commercially Available Aneurysm Flow Modulating Devices
3.4 Current Market Situation
3.5 In-Development Aneurysm Flow Modulating Devices
3.6 Market Evolution Scenarios
3.7 Market Forecast

4. Endovascular Aneurysm Repair Device Market

4.1 World Market for Endovascular Aneurysm Repair Devices
4.2 US Market for Endovascular Aneurysm Repair Devices
4.3 European Market for Endovascular Aneurysm Repair Devices
4.4 Asia-Pacific Market for Endovascular Aneurysm Repair Devices
4.5 Market Segmentation Based on Aneurysm Location
4.6 Leading Companies & Their Products
4.7 Leading Companies Market Shares
4.8 Paradigm Shift & Strategic Opportunities

5. Endovascular Abdominal Aortic Aneurysm Repair Device Market

5.1 Market Size & Growth Rates
5.2 Leading Companies Market Shares
5.3 Current Generation Stent Grafts
5.4 Fenestrated Stent Grafts
5.5 Branched Stent Grafts
5.6 Flow Modulating Devices

6. Endovascular Thoracic Aortic Aneurysm Repair Device Market

6.1 Market Size & Growth Rates
6.2 Leading Companies Market Shares
6.3 Thoraco-Abdominal Aneurysms - Unmet Needs & Opportunities
6.4 Aortic Dissection - Unmet Needs & Opportunities

7. Endovascular Cerebral (Intracranial) Aneurysm Repair Device Market

7.1 Coils, Stents & Liquid Embolics
7.2 Promise of Flow Modulating Devices
7.3 Market Size & Growth Rates
7.4 Leading Companies Market Shares

8. Endovascular Peripheral Aneurysm Repair Device Market

8.1 Science & Technology Update
8.2 Current Market Situation

9. Profiles of Main Companies

9.1 Abbott Vascular
9.2 Aptus Endosystems
9.3 Balt
9.4 Biotronik
9.5 Boston Scientific
9.6 Bolton Medical
9.7 Braile Biomedica
9.8 Cardiatis
9.9 Chestnut Medical
9.10 Cook Medical
9.11 Endologix
9.12 EV3
9.13 Gore Medical
9.14 Inspire MD
9.15 ITGI Medical
9.16 Johnson & Johnson
9.17 Jotec
9.18 Lemaitre Vascular
9.19 Lombard Medical
9.20 Medtronic
9.21 Merlin MD
9.22 MicroVention
9.23 Micrus
9.24 Nano Endoluminal
9.25 NeuroVasx
9.26 Surpass Medical
9.27 Nellix Endovascular
9.28 Terumo Vascular
9.29 Trivascular2
9.30 University of Buffalo
9.31 Valor Medical

List of Tables & Figures

1. Aneurysm Initiation, Progression & Rupture
2. Aneurysm Hemodynamics & Arterial Vascular Remodeling
3. Flow Modulation Concept for Aneurysm Repair
4. Commercially Available Aneurysm Flow Modulating Devices
5. Aneurysm Flow Modulating Devices - Market Segmentation 2009
6. Aneurysm Flow Modulating Devices - Companies Market Share 2009
7. In-Development Aneurysm Flow Modulating Devices
8. Market Evolution Scenarios (2009 - 2015)
9. Aneurysm Flow Modulating Device Market Forecast (2009 - 2015)
10. World Endovascular Aneurysm Repair Device Market (2003-2008)
11. EVAR Market Segmentation based on Aneurysm Location (2008)
12. Endovascular Aneurysm Repair – Geographic Segmentation (2008)
13. US Endovascular Aneurysm Repair Device Market (2003-2008)
14. US Market Segmentation based on Aneurysm Location (2008)
15. European Endovascular Aneurysm Repair Market (2003-2008)
16. European Market Segmentation based on Aneurysm Location (2008)
17. Asia Pacific Endovascular Aneurysm Repair Market (2003-2008)
18. European Market Segmentation based on Aneurysm Location (2008)
19. List of Leading Companies in the Space and Their Product Offerings
20. Leading Companies Market Shares
21. Horizontal Integration of Leading Companies Product Lines
22. Aortic Intervention – New Cases – Developed World View
23. Aortic Intervention – Number of Procedures
24. Endovascular AAA Repair Market Revenue (2003 – 2008)
25. Endovascular AAA Repair Market Geographic Segmentation (2008)
26. Endovascular AAA Repair Leading Companies Market Shares (2008)
27. AAA Endografts First Generation Device Failures
28. Commercially Available Endovascular AAA Repair Devices
29. In-Development Endovascular AAA Repair Devices
30. Endovascular TAA Repair Market Revenue (2003 – 2008)
31. Endovascular TAA Repair Market Geographic Segmentation (2008)
32. Endovascular TAA Repair Market Companies Market Shares (2008)
33. Commercially Available Endovascular TAA Repair Devices
34. Endovascular Cerebral Aneurysm Repair Market (2003 – 2008)
35. Endovascular Cerebral Aneurysm Repair Geographic Segmentation
36. Endovascular Cerebral Aneurysm Repair Companies Market Shares
37. Commercially Available Coils and Liquid Embolic Systems
38. Commercially Available Stents for Assisted Coil Insertion
39. Commercially Available and In-Development Flow Diverting Devices
40. Worldwide Overview of New Stroke Cases
41. Global Interventional Procedures for Hemorrhagic Stroke
42. Endovascular Cerebral Aneurysm Repair Device Segments Shares
43. Leading Companies & Products Competing in the Cerebral Space
44. Covered Stents for Repair of Popliteal Artery Aneurysms
45. Patency Rates for Covered Stents in Popliteal Artery Aneurysms
46. Boston Scientific NeuroVascular Revenue (2003 – 2008)
47. Endologix Revenue (2004 – 2008)
48. EV3 NeuroVascular Business Unit Revenue (2003 – 2008)
49. Micrus Endovascular Revenue (2003 – 2008)


Companies Mentioned - Abbott Vascular - Aptus Endosystems - Balt - Biotronik - Boston Scientific - Bolton Medical - Braile Biomedica - Cardiatis - Chestnut Medical - Cook Medical - Endologix - EV3 - Gore Medical - Inspire MD - ITGI Medical - Johnson & Johnson - Jotec - Lemaitre Vascular - Lombard Medical - Medtronic - Merlin MD - MicroVention - Micrus - Nano Endoluminal - NeuroVasx - Surpass Medical - Nellix Endovascular - Terumo Vascular - Trivascular2 - University of Buffalo - Valor Medical


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