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Who's Afraid of the Patent Cliff?

Informa Healthcare, Aug 2008, Pages: 16


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Nobody needs a crystal ball to predict the turn of the next decade as a landmark chapter in the pharmaceutical industry’s story book. The period from 2010-12 in particular will see a wave of patent expiries leave gaping holes in the balance sheets of some of the research-based industry’s bellwether companies. This Scrip analysis reviews the industry’s prospects as it squares up to one of the greatest challenges it has ever faced.

Key topics covered:

- The patent cliff: how much is at stake?
- Big name products in the firing line
- Evaluating the generic threat
- Getting less for more? Pharmaceutical R&D vs marketing spend
- Patent litigation 'a fact of life'
- Case studies: Pfizer/Ranbaxy and AstraZeneca's Seroquel
- Maximising the value of assets
- Health technology assessment (HTA) raising the bar for line extensions
- Evolving healthcare models
- Buying into generics = sleeping with the enemy? Novartis/Hexal; Sanofi-Aventis/Zentiva; Daiichi Sankyo/Ranbaxy
- The biosimilars political debate in the US;
- Novel R&D models
- Personalisation of medicine



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