|
|
 |
|
Viewing report
|
|
|
|
Bioinformatics for Glycobiology and Glycomics: An Introduction
John Wiley and Sons Ltd, Dec 2009, Pages: 494
This book is the first to be dedicated to the bioinformatics of carbohydrates and glycoproteins. It provides an introduction to this emerging field of science both for the experimentalist working in glycobiology and glycomics, and also for the computer scientist looking for background information for the development of highly sophisticated algorithmic approaches. The book provides an overview of the state-of-the-art in the field, with reviews on databases, and the tools in use for analysis, interpretation, and prediction of the structures of complex carbohydrates, and demonstrates the value of bioinformatics for glycobiology.
The availability of comprehensive databases and corresponding bioinformatics tools, to access and analyse the large amounts of experimental data relating to the structure of carbohydrates, will be a prerequisite for the success of the large-scale glycomics projects that aim to decipher new, so far unknown, biological functions of glycans. Efficient bioinformatics descriptions and tools can considerably enhance the efficiency of glycomics research, in terms of data quality, analysis and experimental costs.
For a complete understanding of the molecular processes in which carbohydrates are involved, such as protein–carbohydrate interactions and the impact of glycosylation on protein function, knowledge of the 3D structure of the carbohydrate, the protein–carbohydrate complex, or the glycoprotein is often indispensable. This book provides a thorough introduction into methods used for conformational analysis of carbohydrates.
Key features:
- Describes bioinformatic approaches to handle carbohydrate-active enzymes and glycosylation.
- Provides an overview on bioinformatics tools that facilitate analysis of carbohydrate structures.
- Gives introduction into molecular modelling of carbohydrate 3D structure and carbohydrates contained in the Protein Databank.
- Assumes only a basic knowledge of biology and bioinformatics.
Recent advances in sequence determination for complex carbohydrates should lead to the generation of large amounts of data relating to their sequence and structure. Interpretation of this sequence information will require new bioinformatics tools. Several groups worldwide are defining the basic principles of how best to encode and store the structures of complex carbohydrates. The automated interpretation of experimental data, especially mass spectra, is currently the most active area of research. The availability of comprehensive databases and corresponding bioinformatics tools to access and analyse the data will be a prerequisite for the success of the large-scale glycomics projects that aim to decipher new, so far unknown, biological functions of glycans. This book is the first dedicated to the bioinformatics of carbohydrates and glycoproteins. It provides a state of the art overview and demonstrates the value of bioinformatics for glycobiology, not simply as a review of databases and tools but rather as an introduction to a new branch of glycobiology. Efficient bioinformatics descriptions and tools can considerably enhance the efficiency of glycomics research, in terms of data quality, analysis and experimental costs. The objective of the book is to illustrate ways to use bioinformatics to enhance glycomics data mining and improve glycomics analysis.
Product samples
A sample for this product is available. Please Login/Register to download this sample.
Customers who bought this item also bought
DNA Sequencing - Technologies, Markets and Companies
Proteomics - Technologies, Markets and Companies
The Global Bioinformatics Market: Market Size, Forecasts and Company Profiles
Bioinformatics Market - Advanced Technologies, Global Forecast and Winning Imperatives (2009 - 2014)
Biochips and Microarrays - Technologies, Markets and Companies
BSL3 and BSL4 Agents: Proteomics, Glycomics, and Antigenicity
Biomacromolecules: Introduction to Structure, Function and Informatics
Tag-based Next Generation Sequencing
Biomarkers - Technologies, Markets and Companies
Innovations in Bioinformatics: Emerging Tools for Drug Discovery and Development
|
|
|
|
