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Global Active Pharmaceutical Ingredients Market: An Outlook

Frost & Sullivan, Sep 2009, Pages: 51


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This study provides an overview of the global active pharmaceutical ingredients market. It is broadly divided into three chapters- API market analysis, therapeutic-area wise analysis and recommendations to market participants.

This Frost & Sullivan research service titled Global Active Pharmaceutical Ingredients Market: An Outlook provides the market overview, Market Engineering research, and therapeutic area-wise opportunity analysis of the global active pharmaceutical ingredients (APIs) market. In this research, Frost & Sullivan's expert analysts thoroughly examine the following applications: cardiovascular diseases, central nervous system disorders, diabetes, oncology and respiratory disorders.

Market Overview

Niche Growth Segments to Offer Potential for Participants in the Global Active Pharmaceutical Ingredients Market

Niche growth segments hold significant potential for the APIs market participants, as they are confronted by several challenges such as overcapacity, industry consolidation and lack of capability differentiation. The API market, traditionally dominated by small molecule drugs, is currently witnessing a rapid shift towards biopharmaceuticals. As the market moves from a blockbuster model to more focused niche drugs, there will be many new opportunities for API manufacturers.

'Participants from emerging markets such as India, China, and Eastern Europe are consolidating their position as preferred sourcing partners, thereby boosting the API market,' says the analyst of this research. 'These participants have specialized process chemistry skills, besides low production and labour costs, giving them an edge in API manufacturing and distribution.' While companies from India have excellent chemistry skills due to their well-established generics exports industry, companies from China are preferred for their bulk drug and intermediate sourcing. These countries are leveraging their inherent strengths to emerge as strong contenders in the global market.

Product Differentiation to be the Most Significant Key to Success in the API Market

The decline in R&D productivity is the most significant factor restraining the growth of the API market. Over the past decade, there has been a marked fall in the number of blockbusters entering the market. In the 1990s, successfully relied on the blockbuster model. However, due to an increasing failure rate in late-stage drugs, the pharmaceutical industry is witnessing a shift towards generics and biopharmaceuticals. As global conditions become more challenging, larger pharmaceutical companies are likely to refrain from investing heavily in developing new small molecule drugs, thereby affecting the API market in the long term.

'Product differentiation is expected to be the most significant key to success in the API market.', explains the analyst. 'Investment in early-stage technology and product platforms can help market participants have a competitive advantage.' Pure-play API vendors and contract manufacturing organisations (CMOs) should follow a two-pronged strategy to differentiate themselves from competition. Firstly, instead of merely focusing on reducing the overall yield of a given API or improving certain steps in a custom synthesis, vendors should aim at investing in early-stage technology and product platforms for a competitive edge. Secondly, the sourcing of APIs is often a critical decision in the overall development process, and companies have begun to realise the importance of tying up with local manufacturers in emerging markets to tap into their cost advantage and produce high-quality, low-cost products. Finally, the provision of value-added services, such as intermediate procurement and production, and dosage form are expected to aid in consolidating vendor-customer relationships, thereby making the overall API outsourcing process a strategic decision.

Application Sectors

Expert Frost & Sullivan analysts thoroughly examine the following applications sectors in this research:

- Cardiovascular diseases
- Central nervous system disorders
- Diabetes
- Oncology
- Respiratory disorders


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