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Pulmonary Edema. Lung Biology in Health and Disease

Informa Healthcare, April 1998, Pages: 688

This comprehensive reference illuminates recent breakthroughs in understanding the pathogenesis, pathophysiology, and resolution of pulmonary edema, and highlights new therapeutic options for managing patients with accompanying acute respiratory failure.
Pooling the experience of more than 40 international experts in the field, Pulmonary Edema

- reviews state-of-the-art methods and technology for measuring transvascular fluid balance and protein flux in the lung

- presents the radiographic, clinical, and laboratory features of pulmonary edema in critically ill patients

- outlines the alveolar epithelial fluid transport capacity of the alveolar epithelium in removing edema fluid from the lung

- explains how sepsis, pneumonia, aspiration, and major trauma contribute to pulmonary edema

- assesses new approaches for treating both hydrostatic and increased-permeability pulmonary edema

- discusses the potential role of aquaporins in the formation and resolution of pulmonary edema

- describes how positive pressure ventilation may amplify the degree of acute lung injury

- details the mechanisms for removal of excess fluid and protein from the airspaces and interstitium of the lung

- examines impending clinical applications of recent basic findings in treating pulmonary edema and acute respiratory distress syndrome

- and more!
Featuring more than 2700 references, drawings, photographs, and equations, Pulmonary Edema is suitable for pulmonary disease, critical care, and surgical critical care specialists, chest physicians, respiratory physiologists, cardiologists, respiratory therapists, anesthesiologists, anatomists, cell biologists, cardiothoracic surgeons, general internists, pediatricians, and graduate and medical school students in these disciplines.

Pathophysiology and Clinical Assessment

Physiological Basis of Pulmonary Edema, Jahar Bhattacharya
Histopathology of Pulmonary Edema and the Acute Respiratory Distress Syndrome, Kurt H. Albertine
Radiographic Manifestations of Pulmonary Edema, Robert D. Suh and Denise R. Aberle
Evaluation of Pulmonary Endothelial Barrier Function: Quantifying Pulmonary Edema and Lung Injury, Daniel P. Schuster

Specific Clinical Etiologies

Hydrostatic Pulmonary Edema, Mary I. Townsley
Increased-Permeability Pulmonary Edema from Sepsis/Endotoxemia, Ivan M. Robbins, John H. Newman, Kenneth L. Brigham
Pulmonary Edema Associated with Bacterial Pneumonia, Jeanine P. Wiener-Kronish, Teiji Sawa, Kiyoyasu Kurahashi, Maria Ohara, and Michael A. Gropper
Aspiration Syndromes: Acid, Salt Water, and Fresh Water, Hans G. Folkesson and Richard M. Effros
Increased-Permeability Edema Following Hemorrhagic and Traumatic Shock, Katharina Modelska and Jean-François Pittet
Neurogenic Pulmonary Edema, Michael B. Maron and Charles F. Pilati
High-Altitude Pulmonary Edema, Herbert N. Hultgren
Mechanisms Underlying Ischemia/Reperfusion Injury of the Lung, John E. Heffner
Lung Injury Induced by Mechanical Ventilation, Jacob Iasha Sznajder, Karen M. Ridge, Georges Saumon, and Didier Dreyfuss

Resolution and Treatment

Resolution of Alveolar Edema: In Vivo Studies, Ethan P. Carter, Chrystelle Garat, Tsutomu Sakuma, Yibing Wang, Andre R. Campbell, and Michael A. Matthay
Biophysical Properties of Na+ Channels in Alveolar Epithelial Cells, Yi Guo, Michael D. DuVall, and Sadis Matalon
Na,K-ATPase and the Clearance of Pulmonary Edema Fluid, David H. Ingbar, Christine H. Wendt, and Edward D. Crandall
Use of Isolated Lungs to Clarify the Mechanisms by Which Alveolar Edema Is Resolved, Georges Saumon
Water Transport and Molecular Water Channels in Lung, Alan S. Verkman
Alveolar Protein Clearance, Randolph H. Hastings and Kwang-Jin Kim
Treatment of Acute Pulmonary Edema and the Acute Respiratory Distress Syndrome, Yves Berthiaume, Lorraine B. Ware, and Michael A. Matthay

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