Antivirals Against AIDS

Informa Healthcare, July 2000, Pages: 344

This volume, devoted specifically to antiviral therapy, describes current practices used to treat HIV-infected patients, clarifies the use and suitability of animal model systems for the study and evaluation of drug performance, and reveals novel treatments and vaccines in early developmental stages.
Highlights gene therapy and nanoparticle technology!
Including more than 1375 references that encourage and facilitate further research, Antivirals Against AIDS

- addresses problems encountered with resistance to antiretroviral treatments

- details second- and third-generation approaches to anti-HIV therapies targeting HIV reverse transcriptase and protease proteins

- examines inhibiting the spread of HIV by pinpointing appropriate receptors for entry into cells

- considers unique delivery systems for the uptake of drugs into individual cells as deterrents to viral replication

- discusses the prospects of inexpensive, easily deliverable vaccines

- summarizes the benefits and shortcomings of current therapeutic regimens

- and more!
Exploring why HIV is difficult to eradicate and how its special properties and characteristics influence control of the infection, Antivirals Against AIDS is an interdisciplinary reference of interest to infectious disease specialists, immunologists and virologists, hematologists, primary care physicians and internists, and medical school students in these disciplines.

The Retrovirus Family and the Human Immunodeficiency Virus: Molecular Targets for Therapy and Existing Drugs
Helga Rübsamen-Waigmann
Antiretroviral Treatment of HIV Infection
Stefan Mauss and Hans Jäger
Antivirals and Resistance
Ursula Dietrich and Andreas Immelmann
Reverse Transcriptase Inhibitors as Anti-HIV Drugs
Erik De Clercq
Inhibitors of HIV Protease
Sally Redshaw and Gareth J. Thomas
HIV Vaccine Research
Patricia E. Fast and Alan M. Schultz
Gene Therapy of HIV Infection
Stefan A. Klein, Christian Klebba, Manuel Grez, and Dieter Hoelzer
Antagonism of Chemokine Receptors in Preventing Infection by HIV
Amanda E. I. Proudfoot, Timothy N. C. Wells, and Alexandra Trkola
Drug Targeting with Colloidal Carriers for Antiretroviral Agents
Hagen von Briesen, Peter Ramge, and Jörg Kreuter
Nonhuman Primate Models for Testing Anti-HIV Drugs
Koen K. A. Van Rompay and Marta L. Marthas

Ronald E. Unger
Jorg Kreuter
Helga Ruubsamen-Waigmann

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