Evolution after Gene Duplication

  • ID: 1340343
  • October 2010
  • 350 Pages
  • John Wiley and Sons Ltd
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The first book to examine gene duplication across all levels of biological organization

The duplication of genes and genomes has long been postulated to have played a major role in the rise of biological novelty through evolution of new function and gene expression patterns. This biological novelty is represented on multiple levels, ranging from new genes, proteins, network interactions, and expression patterns to new species. Evolution after Gene Duplication is the first venue in which gene duplication is examined across all levels of biological organization in order to present a comprehensive picture of the mechanistic process by which gene duplication may have played a part in generating biodiversity.

Bringing together experts from various disciplines, the book:

- Links the evolutionary process associated with gene duplication through structure to function
- Describes the link between the process of gene duplication and protein structure
- Presents a procedure for linking changes in gene copy number through evolution to functional and gene expression evolution
- Offers an overview of model and parsimony–based approaches for gene tree/species tree READ MORE >

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1 Understanding Gene Duplication through Biochemistry and Population Genetics (David A. Leberles, Grigory Kolesov, and Katharina Dittmar).

2 Functional Divergence of Duplicated Genes (Takashi Makino, David G. Knowles, and Aoife McLysaght).

3 Duplication Retention After Small– and Large–Scale Duplications (Steven Maere and Yves Van de Peer).

4 Gene Dosage and Duplication (Fyodor A. Kondrashov).

5 Myths and Realities of Gene Duplication (Austin L. Hughes and Robert Friedman).

6 Evolution After and Before Gene Duplication? (Tobias Sikosek and Erich Bornberg–Bauer).

7 Protein Products of Tandem Gene Duplication: A Structural View (William R. Taylor and Michael I. Sadowski).

8 Statistical Methods for Detecting Functional Divergence of Gene Familiies (Xun Gu).

9 Mapping Gene Gains and Losses Among Metazoan Full Genomes Using an Integrated Phylogenetic Framework (Athanasia C. Tzika, Raphaël Helaers, and Michel C. Milinkovitch).

10 Reconciling Phylogenetic Trees (Oliver Eulenstein, Snehalata Huzurbazar, and David A. Liberles).

11 On the Energy and Material Cost of Gene Duplication (Andreas Wagner).

12 The Fate of a Duplication in a Network Context (Orkun S. Soyer).

13 Evolutionary and Functional Aspects of Genetic Redundancy (Ran Kafri and Tzachi Pilpel).

14 A Phylogenomic Approach to the Evolutionary Dynamics of Gene Duplication in Birds (Gene L. Organ, Matthew D. Rasmussen, Maude W. Baldwin, Manolis Kellis, and Scott V. Edwards).

15 Gene and Genome Duplications in Plants (Pamela S. Soltis, J. Gordon Burleigh, Andre S. Chanderbali, Mi–Jeong Yoo, and Douglas E. Soltis).

16 Whole Genome Duplications and the Radiation of Vertebrates (Shigehiro Kuraku and Axel Meyer).


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"This up–to–date overview of theory and mathematical models along with practical examples is suitable for scientists across various levels of biology as well as instructors and graduate students." (Forbes.com, 27 October 2010)

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