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Exploring Structural Biology: Tools & Techniques Used in the Study of Membrane Protein Structure
BioInformatics, LLC, Oct 2010
While the study of membrane proteins is not a new field, technological limitations and challenges have plagued researchers for decades. Recent technological advancements and the introduction of computational approaches to the analysis of membrane components have brought new life to membrane structural biology, creating opportunities for suppliers of membrane structural biology products.
Unique and innovative methods are being developed for membrane protein extraction, characterization, and structure determination of biologically significant membrane proteins, opening doors in the membrane structural biology market. Scientists are applying techniques such as in silico computational analysis, isoelectric focusing, one and two-dimensional gel electrophoresis, high-performance liquid chromatography (HPLC), nuclear magnetic resonance (NMR), and mass spectrometry (MS) to better understand the structure and functional interactions of cellular membrane proteins, leading to the design of more effective therapeutics for many human diseases. The growing number of platforms, products and tools offered by niche membrane biology companies, and major life science companies are drawing in more and more researchers previously restricted to studying soluble proteins.
This report introduces Exploring Structural Biology: Tools and Techniques Used in the Study of Membrane Protein Structure to provide a roadmap for suppliers who seek to explore new market opportunities. This report identifies technologies and areas with the highest potential for rapid growth in the membrane structural biology market, i.e., research focuses, approaches and techniques, in silico computational tools used, protein extraction methods, integral protein analysis methods, and HPLC, NMR and MS platforms.
In addition, Exploring Structural Biology: Tools and Techniques Used in the Study of Membrane Protein Structure focuses on anticipated technology platform and product purchasing trends to assist suppliers with long-term strategies that will yield a viable market position. Detailed market share information and projections are provided by technology type, along with membrane structural biology research budget data and expected changes through 2011. Suppliers will be able to use this report to anticipate areas of product growth and saturation.
OBJECTIVES:
The primary objective of this report is to provide life science product suppliers with insight into the market for tools used in membrane protein structural biology research:
- Estimate average laboratory spending on membrane protein structural biology research and growth by individual product categories
- Understand the workflow and tools used in membrane protein structural biology research including such methods as HPLC, mass spectrometry, NMR, computational methods, and electrophoresis based methods
- Identify key decision drivers in choosing suppliers for tools used in membrane protein structural biology research
- Asses supplier share by usage for different product categories
- Key areas of research interest related to membrane structural biology
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