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Lung Cancer Drug Futures 2010
Espicom Business Intelligence Ltd, Oct 2010, Pages: 252
Although a plethora of platinum-based chemotherapy combinations may be prescribed for the treatment of non small cell lung cancer (NSCLC) the market is currently driven by chemotherapeutic agents such as taxanes and antimetabolites, and the increasing use of targeted therapies. Some of the newer chemotherapy agents such as Eli Lilly’s Gemzar and Alimta have become the standard of care in combination with cisplatin or carboplatin and may be used in addition to or instead of the taxanes Taxotere or Taxol/generic paclitaxel.
The lung cancer market is set for radical change. A number of current first-line therapies will become subject to generic competition in the short term. Although chemotherapy will continue to play a significant if diminishing role, industry attention is firmly on the better-tolerated biologics which are already setting the pace in the market and whose influence will grow over the coming years. In 2007, chemotherapy treatments accounted for 68% of the market but are forecast to account for only 32% by 2014, whereas targeted treatments are forecast to increase from 30% to 60% over the same period.
As researchers begin to understand the processes involved in NSCLC formation, several new targeted therapies have evolved which modulate growth factor pathways. For example, Roche’s small-molecule tyrosine kinase inhibitor Tarceva (erlotinib) and its best selling anti-angiogenic VEGF inhibitor Avastin (bevacizumab) are gaining credence in second- and first-line therapy for advanced disease, respectively.
NOW YOU CAN STAY IN TOUCH WITH THE DEVELOPMENTS WHICH MATTER:
This all new web service from Espicom, Lung Cancer Drug Futures, assesses the future prospects for market success for individual drugs. Based on independent research and proprietary analysis, each product assessed brings the prospects for a product into clear focus. Best of all, each drug is regularly reviewed ensuring that latest developments are incorporated for you to see.
WITH EACH KEY DRUG ANALYSED IN THIS SERVICE YOU CAN:
- Track the drug’s progress and stay abreast of developments
- Understand the drug’s novelty and mode of action
- Evaluate the strength of the company developing/producing the drug
- Review opportunities and challenges with Espicom’s unique 5-point competitive assessment
- Know the launch timeframe for new products or indications
- Be aware of promising mid-stage development candidates
- Estimate future revenues with original 5-year forecasts for launched and leading pipeline candidates
- Review significant clinical trial results
STRUCTURED ANALYSIS OF KEY DRIVERS AND DAMPENERS OF SUCCES:
For each product analysed there is an extensive and standardised review of the factors which can affect its clinical and commercial performance. Those factors include…
- Novelty/rationale for mechanism of action
- Current status
- Proof of concept/clinical data
- Development risks
- Company expertise
- Competition within the market-place
- Sales forecast (for key late-stage and launched products)
- Competitor ratio analysis score
- Clinical trial results
OVER 45 CURRENT DRUGS COVERED:
Because this service is continually updated, products will be added, deleted or enhanced in response to ongoing developments throughout the course of your licence. From time-to-time drug profiles may be removed from the service for essential updating.
Approved
Bevacizumab
Docetaxel
Erlotinib
Gefitinib
Gemcitabine
Pemetrexed disodium
Paclitaxel
Phase III
Aflibercept
Belagenpumatucel-L
BIBF 1120
BIBW 2992
Canfosfamide
Crizotinib
Figitumumab
MAGE-A3
Motesanib diphosphate
Necitumumab
PF-02341066
PF-299804
Sorafenib
Stimuvax
Sunitinib malate
Talactoferrin alpha
Vadimezan
Phase II
Arenegyr
ARQ 197
AT-101
Axitinib
AZD6244
Bavituximab
Bortezomib
CDP501
CDP791
Cediranib
Cixutumumab
Conatumumab
Custirsen sodium
Dulanermin
Enzastaurin
Gimatecan
Ipilimumab
Linifanib
lxabepilone
MGCD265
OGX-011
Pazopanib
PD-3512676
Pertuzumab
PF-3512676
Ramucirumab
Sagopilone
STA-9090
TG4010
Phase I/II
Retaspimycin
Tivozanib
XL184
Phase I
Everolimus
IMO-2055
Naptumomab estafenatox
Suspended or Discontinued
ABT-751
Cetuximab
Mapatumumab
NOV-002
Paclitaxel
poliglumex
Vandetanib
CLEAR, CONCISE, AND ORIGINAL ANALYSIS GIVES YOU KEY PRODUCT INSIGHTS:
The Cancer Drug Futures incorporate the latest analysis from our in-house team of life scientists and statisticians across a range of cancer areas. Their research builds upon the analysts established knowledge base of up-to-date intelligence on thousands of pharmaceutical manufacturers and research companies, backed up by a fifteen years’ of archive material.
Taking all aspects of the market into account, from clinical trials, deals and alliances to company financial performance and drug sales, the analysis and forecasting that contributes to the Cancer Drug Futures is standardised across each individual launched product or drug candidate and is founded upon a diligent and thorough research process.
With the Cancer Drug Futures you can easily evaluate the prospects of the drugs of interest to you and discover its progress in each indication. Each report provides individual and highly-detailed analysis of the drug, looking at the key factors affecting its future performance in the marketplace.
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