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Alpha6 Beta4 Integrin Signaling Pathway in Oncology Drug Pipeline Update

  • ID: 1537322
  • February 2016
  • Region: Global
  • Bioseeker
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The Alpha6 Beta4 Integrin signaling pathway activates the PI 3-kinase/Akt, MAPK/NFkB and SMAD signaling modules.

There are today 370 companies plus partners developing 510 Alpha6Beta4 integrin pathway targeting drugs in 1683 developmental projects in cancer. In addition, there are 2 suspended drugs and the accumulated number of ceased drugs over the last years amount to another 203 drugs. Alpha6 Beta4 Integrin Signaling Pathway In Oncology Drug Pipeline Update lists all drugs and gives you a progress analysis on each one of them. Identified drugs are linked to 185 different targets. All included targets have been cross-referenced for the presence of mutations associated with human cancer. To date 182 out of the 183 studied drug targets so far have been recorded with somatic mutations. The software application lets you narrow in on these mutations and links out to the mutational analysis for each of the drug targets for detailed information. All drugs targets are further categorized on in the software application by 43 classifications of molecular function and with pathway referrals to BioCarta, KEGG, NCI-Nature and NetPath.

How May Drug Pipeline Update Be of Use?
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