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Alpha6 Beta4 Integrin Signaling Pathway in Oncology Drug Pipeline Update 2014 Product Image

Alpha6 Beta4 Integrin Signaling Pathway in Oncology Drug Pipeline Update 2014

  • ID: 1537322
  • October 2014
  • Region: Global
  • Bioseeker

The Alpha6 Beta4 Integrin signaling pathway activates the PI 3-kinase/Akt, MAPK/NFkB and SMAD signaling modules.
There are today 245 companies plus partners developing 395 Alpha6Beta4 integrin pathway targeting drugs in 1391 developmental projects in cancer. In addition, there are 2 suspended drugs and the accumulated number of ceased drugs over the last years amount to another 177 drugs. Alpha6 Beta4 Integrin Signaling Pathway In Oncology Drug Pipeline Update lists all drugs and gives you a progress analysis on each one of them. Identified drugs are linked to 165 different targets. All included targets have been cross-referenced for the presence of mutations associated with human cancer. To date 162 out of the 163 studied drug targets so far have been recorded with somatic mutations. The software application lets you narrow in on these mutations and links out to the mutational analysis for each of the drug targets for detailed information. All drugs targets are further categorized on in the software application by 36 classifications of molecular function and with pathway referrals to BioCarta, KEGG, NCI-Nature and NetPath.

How May Drug Pipeline Update Be of Use?
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