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Wnt Signaling Pathway in Oncology Drug Pipeline Update 2014 Product Image

Wnt Signaling Pathway in Oncology Drug Pipeline Update 2014

  • Published: March 2014
  • Region: Global
  • Bioseeker

Abnormalities in the Wnt signaling pathway are associated with a large variety of human malignancies including tumors of breast, colon, pancreas, liver and bone.
There are today 178 companies plus partners developing 197 Wnt pathway targeting drugs in 677 developmental projects in cancer. In addition, there are 3 suspended drugs and the accumulated number of ceased drugs over the last years amount to another 103 drugs. Wnt Signaling Pathway In Oncology Drug Pipeline Update lists all drugs and gives you a progress analysis on each one of them. Identified drugs are linked to 190 different targets. All included targets have been cross-referenced for the presence of mutations associated with human cancer. To date 186 out of the 187 studied drug targets so far have been recorded with somatic mutations. The software application lets you narrow in on these mutations and links out to the mutational analysis for each of the drug targets for detailed information. All drugs targets are further categorized on in the software application by 41 classifications of molecular function and with pathway referrals to BioCarta, KEGG, NCI-Nature and NetPath.

How May Drug Pipeline Update Be of Use?
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Delivery Format: Desktop App plus Online Access to Updates (One Year)

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