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Metabolic Syndrome
Future Medicine Ltd, Dec 2010, Pages: 78
The increasing worldwide prevalence of metabolic syndrome represents an important healthcare issue across the world. Metabolic syndrome is most frequently defined by a presence of certain traits, including abdominal obesity, insulin resistance, dyslipidaemia, elevated blood pressure and pro-thrombotic and pro-inflammatory states. It is rather difficult to develop universally effective drugs that act on single targets within the complex pathological network. A more feasible approach might be to manage multiple elements of the pathomechnism and/or to eliminate or minimize risk factors.
This Special Focus Issue of the peer-reviewed journal Future Medicinal Chemistry features 9 manuscripts from respected researchers in the field including '‘Energy expenditure genes’ or ‘energy absorption genes’: a new target for the treatment of obesity and Type II diabetes' and 'Targeted therapies of the LKB1/AMPK pathway for the treatment of insulin resistance'. The issue highlights new achievements related to the developement of new therapies for metabolic syndrome and its important disease components.
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