Comprehensive Handbook of Iodine. Nutritional, Biochemical, Pathological and Therapeutic Aspects

Elsevier Science and Technology, March 2009, Pages: 1334

Over two billion people worldwide are at risk for the spectrum of disorders known as "The Iodine Deficiency Disorders." 1-10% will suffer cretinism; 5-30% will have some sort of brain damage or neurological impairment and 30-70% will be hypothyroid.

The causes of iodine deficiencies can be considered from both simplistic and more complex perspectives: From the leaching of iodine from soil resulting in crops with low iodine content to malnutrition resulting in impaired iodine absorption. Poor dietary diversification and impoverished socio-economic development can also lead to iodine deficiencies.

Although it is possible to diagnose and treat deficiencies, there is still an ongoing dialogue regarding the detailed molecular pathology of iodine homeostatis, how hypothyroidism impacts the body tissues, and efficient diagnosis and treatment of the Iodine Deficiency Disorders.

This Handbook provides a resource of information on the various pathways and processes based on different countries or diseases. Because there is a constant flow of new information on iodine and related disorders, the goal of this Handbook is to provide a base of scientific information upon which additional knowledge can be applied.

Key Features:
-Provides important information on one of the most common micro-nutrient deficiencies in the world, the most important "single nutrient-multiple consequences" paradigm today
-Includes information on iodine-related diseases, including those that are common, preventable and treatable
-Provides insight from a broad perspective of viewpoints -- from subcellular transports to economic impact

Part I: Forward by the ICIDD and WHO
Part II:General Aspects of Iodine Sources and Intakes in the Diet and Main routes of Iodine Metabolism in the Mammal Organism
Part III: Damage and Disease Due to Iodine Deficiency
Part IV: Metabolic Consequences of Hypothyroidism and Other Thyroid Disease
Part V: Damage and Disease Due to Iodine Excess
Part VI: Treatment Regimes
Part VII: Selective Methods Used in Iodine Research

Preedy, Victor R.
Burrow, Gerard N.
Watson, Ronald Ross.

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