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5-Aminosalicylate Therapies in IBD: Opinion Leader Insight into Current & Future Treatment Practices

Sociable Pharma, April 2011, Pages: 150


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5-aminosalicylate therapies form a fundamental part of the treatment of both Crohn's disease and ulcerative colitis. However, while new therapies and data continue to cement the place of 5-ASAs as first-line options for most patients in ulcerative colitis, meta-analysis has undermined doctor confidence in Crohn's disease. Sociable Pharma conducted in-depth primary research in the US and across Europe with key opinion leaders to understand how 5-ASA therapy is currently used in the treatment of inflammatory bowel disease and how it will evolve in the future.

Report highlights:

- SWOT analysis of seven leading 5-ASA therapies, including analysis of relative efficacy and safety profiles as well as dosing and formulation
- Based on key opinion leader interviews in the US and Europe, as well as the ECCO 2011 conference, supplemented with extensive secondary research on medical evidence and guidelines
- Highlights opinion hotspots where treatment approaches differ between physicians and also between the US and Europe, such as the use of once daily oral dosing formulations for 5-ASAs
- Assesses threats from new formulations of corticosteroids and from challenges to the evidence on colorectal cancer prevention
- Detailed visual guides to the treatment of Ulcerative Colitis and Crohn's Disease

Research highlights

SWOT analysis of 7 5-ASA therapies
- Relative efficacy and safety profiles
- Dosing and formulation
- Challenges to additional benefits of colorectal cancer prevention
- Threats from new formulations of corticosteroids

KOL opinion hotspots for UC & Crohn's disease
- Questionable efficacy prompting more doctors to switch to corticosteroids for infrequent relapses
- Severity and extent likely to determine the 5-ASA used
- Use of oral 5-ASAs as first line therapies for UC

Visual guides to UC & Crohn's disease
- 4 Treatment Maps & 48 treatment settings in Crohn's disease
- 4 Treatment Maps & 38 treatment settings in Ulcerative Colitis

Key evidence
- Summarizes of key evidence by line of therapy and class

Summaries of KOL opinion hotspots
- Identifies KOL opinion hotspots by line of therapy and class


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