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Protein Kinases as Drug Targets
John Wiley and Sons Ltd, Feb 2011, Pages: 396
This timely guide to the kinase inhibitor drug development covers the entire drug pipeline, from target identification to compound development and clinical application. On the drug development side, classical medicinal chemistry approaches as well as chemical genomics strategies are discussed. On the clinical side, both current and future therapeutic application areas for kinase inhibitor drugs are covered, with a strong focus on oncology drugs, as this is the most important therapeutic field for these drugs.
With kinase inhibitors being widely seen as the long-sought 'magic bullet' to conquer cancer, this fully comprehensive guide to kinase inhibitor drug development covers the entire drug pipeline from target identification to compound development and clinical application.
Scope:
Volume 1 focuses upon the medicinal chemistry of kinase drugs, from target identification to lead optimization, and contains numerous contributions from large and small pharmaceutical companies.
Volume 2 surveys current and future therapeutic application areas for kinase inhibitor drugs, with a strong focus on oncology drugs, as this is the most important therapeutic field for these drugs.
In addition, all six currently approved kinase inhibitor drugs (small molecules and antibodies) are described, and their performances in clinical practice are discussed.
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