• +353-1-415-1241(GMT OFFICE HOURS)
  • 1-800-526-8630(US/CAN TOLL FREE)
  • 1-917-300-0470(EST OFFICE HOURS)
Top 20 Contract Research Organizations (CRO) - Asia-Pacific, Especially India and China, Positioned to Benefit from Rising Financial and Regulatory Pressures in Western Pharmaceutical Markets - Product Image

Top 20 Contract Research Organizations (CRO) - Asia-Pacific, Especially India and China, Positioned to Benefit from Rising Financial and Regulatory Pressures in Western Pharmaceutical Markets

  • Published: September 2011
  • Region: China, India
  • 114 Pages
  • GBI Research

FEATURED COMPANIES

  • Aptuit
  • Chiltern
  • Covance
  • ICON
  • LAB Research Inc
  • PRA International
  • MORE

“Top 20 Contract Research Organizations (CRO) - Asia-Pacific, Especially India and China, Positioned to Benefit from Rising Financial and Regulatory Pressures in Western Pharmaceutical Markets”, which provides insights into drivers, barriers and trends in the outsourcing of drug development tin the global pharmaceutical and biotechnology industry. The report profiles top 20 contract research organization in Asia-Pacific and provides business overview, business snapshot and the list of alliances made in the period 2005 to 2010

In-depth analysis of the report is based on propriety databases, primary and secondary research and in-house analysis by a team of experts.

Scope

The scope of this report includes:

- Analysis of drivers and barriers in the outsourcing of drug development processes

- Analysis of different functional models in the global CRO industry

- Analysis of key reasons for the pharmaceutical industry to outsource drug development

Reasons to buy

The report will enhance your decision making capability. It will allow you to:

- Identify the top 20 contract research organizations in Asia-pacific

- Identify major international pharmaceutical companies who have made alliances with the Asia-Pacific CROs

- Understand the service offerings of major CROs in the Asia-Pacific

1
1 4
1.1 List of Tables 8
1.2 List of Figures 9
2 Contract Research Outsourcing – Introduction 11
2.1 GBI Research Report Guidance 11
3 Top 20 Contract Research Organizations – Overview 12
3.1 Global Contract Research Outsourcing 12
3.2 The Clinical Research Process 13
3.3 Outsourcing of Clinical Research and Trial Processes 15
3.3.1 Clinical Research Outsourcing Perceived to be a Solution to Problems Such as Rising Costs or Low Productivity 15
3.3.2 Strategic Outsourcing Improves Value for Outsourcing Companies 15
3.4 Key Reasons for Outsourcing to Contract Research Organizations 16
3.4.1 Gaining Cost Reductions is a Key Reason for Contract Research Outsourcing 17
3.4.2 CROs Engaged in Reducing Time to Market in Order to Achieve a Competitive Edge 17
3.4.3 Data Management Allows Biopharmaceutical Companies to Focus on Core Competencies 18
3.4.4 Evolving Risk Sharing Agreements Encourage Biopharmaceutical Companies to Increase Contract Research Outsourcing 18
3.4.5 CROs Help to Improve Clinical Research Quality 18
3.4.6 Small and Medium Biopharmaceutical Companies can Capitalize on the Resources of CROs 19
3.4.7 Biopharmaceutical Companies Benefit from New Technologies 19
4 Contract Research Outsourcing – Geographical Landscape 20
4.1 Emerging Regions in the Global Contract Research Outsourcing Market 21
4.1.1 Latin America 21
4.1.2 Central and Eastern Europe (CEE) 21
4.1.3 India 22
4.1.4 China 23
4.2 Why India and China? 24
4.2.1 Availability of Skilled Manpower 24
4.2.2 Scale of Available Resources for Clinical Development 26
4.2.3 Improved IP Protection in India and China 26
4.2.4 Government Support for the Drug Discovery Development 27
4.2.5 Risk Sharing Agreements: A Step Forward by Indian and Chinese Companies 28
4.3 SWOT Analysis 29
4.4 Conclusion 31
5 Top 20 Contract Research Organizations – Service Models 32
5.1 Contract Research Outsourcing Service Model 32
5.1.1 Fully Integrated Service Model 32
5.1.2 Functional Service Model 33
5.2 Criteria for Selecting a Contract Research Organization 34
6 Top 20 Contract Research Organizations – Market Characterization 35
6.1 The Contract Research Outsourcing Market will be Driven by Demand from Biopharmaceutical Industry 35
6.2 Key Market Drivers 36
6.2.1 Increasing R&D Expenditure and Decreasing Productivity in the Biopharmaceutical Industry 36
6.2.2 Stringent Regulations and Complex Clinical Trials 36
6.2.3 Restriction on Pricing and Reimbursement of Drugs 37
6.2.4 Increasing Number of Clinical Trials 37
6.3 Key Market Restraints/Challenges 38
6.3.1 Quality Concerns 38
6.3.2 Economic Recession 38
6.4 Contract Research Outsourcing – Market Trends 39
6.4.1 Increase in the Number of Services Focusing on Late Stage Clinical Development 39
6.4.2 Globalization of Clinical Research and Trials 39
6.4.3 Strategic Partnerships with CROs 40
6.4.4 Advanced Technology to Enhance Drug Discovery Process 40
7 Top 20 Contract Research Organizations – Competitive Landscape 41
7.1 Overview 41
7.2 Market Share Analysis and Competitive Profiling 42
7.3 Quintiles Transnational Corp. 43
7.3.1 Business Description 43
7.3.2 Snapshot 44
7.3.3 Strategic Consolidations 45
7.3.4 Financial Information 48
7.3.5 SWOT Analysis 49
7.4 Covance 50
7.4.1 Business Description 50
7.4.2 Snapshot 50
7.4.3 Strategic Consolidations 51
7.4.4 Financial Information 52
7.4.5 SWOT Analysis 53
7.5 Pharmaceutical Product Development 54
7.5.1 Business Description 54
7.5.2 Snapshot 54
7.5.3 Strategic Consolidations 55
7.5.4 Financial Information 59
7.5.5 SWOT Analysis 60
7.6 Charles River Laboratories 61
7.6.1 Business Description 61
7.6.2 Snapshot 61
7.6.3 Strategic Consolidations 62
7.6.4 Financial Information 64
7.6.5 SWOT Analysis 65
7.7 PAREXEL 66
7.7.1 Business Description 66
7.7.2 Snapshot 66
7.7.3 Strategic Consolidations 67
7.7.4 Financial Information 69
7.7.5 SWOT Analysis 70
7.8 ICON 71
7.8.1 Business Overview 71
7.8.2 Snapshot 71
7.8.3 Strategic Consolidations 72
7.8.4 Financial Information 73
7.9 INC Research 74
7.9.1 Business Description 74
7.9.2 Snapshot 74
7.9.3 Strategic Consolidations 75
7.9.4 Financial Information 76
7.10 PharmaNet Development Group Inc. 77
7.10.1 Business Description 77
7.10.2 Snapshot 77
7.10.3 Strategic Consolidations 78
7.10.4 Financial Information 79
7.11 PRA International 80
7.11.1 Business Overview 80
7.11.2 Snapshot 80
7.11.3 Strategic Consolidations 81
7.12 CMIC 82
7.12.1 Business Description 82
7.12.2 Snapshot 82
7.12.3 Strategic Consolidations 83
7.12.4 Financial Information 84
7.13 WuXi AppTec 85
7.13.1 Business Description 85
7.13.2 Snapshot 85
7.13.3 Strategic Consolidations 86
7.13.4 Financial Information 87
7.14 Galapagos NV 87
7.14.1 Business Description 87
7.14.2 BioFocus 88
7.14.3 Snapshot 88
7.14.4 Strategic Consolidations 89
7.14.5 Financial Information 94
7.15 LAB Research Inc 95
7.15.1 Business Description 95
7.15.2 Snapshot 95
7.15.3 Strategic Consolidations 96
7.15.4 Financial Information 96
7.16 ReSearch Pharmaceutical Services 97
7.16.1 Business Description 97
7.16.2 Snapshot 97
7.16.3 Strategic Consolidations 98
7.16.4 Financial Information 99
7.17 Omnicare Clinical Research, Inc 99
7.17.1 Business Overview 99
7.17.2 Snapshot 100
7.17.3 Strategic Consolidations 100
7.18 SGS 101
7.18.1 Business Description 101
7.18.2 Snapshot 101
7.19 United BioSource Corporation 102
7.19.1 Business Description 102
7.19.2 Snapshot 102
7.19.3 Strategic Consolidations 103
7.20 BioClinica 104
7.20.1 Business Description 104
7.20.2 Snapshot 104
7.20.3 Strategic Consolidations 104
7.20.4 Financial Information 105
7.21 Aptuit 106
7.21.1 Business Overview 106
7.21.2 Snapshot 106
7.21.3 Strategic Consolidations 107
7.22 Chiltern 108
7.22.1 Business Overview 108
7.22.2 Snapshot 108
7.22.3 Strategic Consolidations 109
7.22.4 Financial Information 110
8 Top 20 Contract Research Organizations - Appendix 111
8.1 Market Definitions 111
8.2 Abbreviations 111
8.3 Research Methodology 112
8.3.1 Coverage 112
8.3.2 Secondary Research 113
8.3.3 Primary Research 113
8.3.4 Expert Panel Validation 113
8.4 Contact Us 114
8.5 Disclaimer 114
8.6 Sources 114

1.1 List of Tables
Table 1: Top 20 Contract Research Organizations, SWOT Analysis – Drug Discovery Market in India and China 30
Table 2: Top 20 Contract Research Organizations, Service Models 32
Table 3: Top 20 Contract Research Organizations, Quintiles, Strategic Consolidations, 2005-2011 45
Table 4: Top 20 Contract Research Organizations, Covance, Strategic Consolidations, 2005-2011 51
Table 5: Top 20 Contract Research Organizations, Pharmaceutical Product Development, Strategic Consolidations, 2006-2011 55
Table 6: Top 20 Contract Research Organizations, Charles River Laboratories, Strategic Consolidations, 2005-2011 62
Table 7: Top 20 Contract Research Organizations, PAREXEL, Strategic Consolidations, 2005-2011 67
Table 8: Top 20 Contract Research Organizations, ICON, Strategic Consolidations, 2010 72
Table 9: Top 20 Contract Research Organizations, INC Research, Strategic Consolidations, 2010 75
Table 10: Top 20 Contract Research Organizations, PharmaNet Development Group Inc, Strategic Consolidations, 2010 78
Table 11: Top 20 Contract Research Organizations, PRA International, Strategic Consolidations, 2010 81
Table 12: Top 20 Contract Research Organizations, CMIC, Strategic Consolidations, 2006-2011 83
Table 13: Top 20 Contract Research Organizations, WuXi PharmaTech, Strategic Consolidations, 2005-2010 86
Table 14: Top 20 Contract Research Organizations, Galapagos, Strategic Consolidations, 2005-2010 89
Table 15: Top 20 Contract Research Organizations, LAB Research Inc, Strategic Consolidations, 2006-2011 96
Table 16: Top 20 Contract Research Organizations, ReSearch Pharmaceutical Services, Strategic Consolidations, 2011 98
Table 17: Top 20 Contract Research Organizations, Omnicare Clinical Research, Strategic Consolidations, 2005-2010 100
Table 18: Top 20 Contract Research Organizations, United BioSource Corporation, Strategic Consolidations, 2005-2010 103
Table 19: Top 20 Contract Research Organizations, BioClinica, Strategic Consolidations, 2011 104
Table 20: Top 20 Contract Research Organizations, Aptuit, Strategic Consolidations, 2005-2011 107
Table 21: Top 20 Contract Research Organizations, Chiltern, Strategic Consolidations, 2006-2011 109

1.2 List of Figures
Figure 1: Top 20 Contract Research Organizations, Global, Basic Services Provided 12
Figure 2: Top 20 Contract Research Organizations, Clinical Research Process 13
Figure 3: Top 20 Contract Research Organizations, Reasons for Outsourcing 16
Figure 4: Top 20 Contract Research Organizations, Clinical Studies by Region, July 2011 20
Figure 5: Top 20 Contract Research Organizations, India & China Talent Pool – Comparison 24
Figure 6: Top 20 Contract Research Organizations, Top 5 Nationalities of Foreign Inventors Named in the PCT (Patent Cooperation Treaty) International Applications Filed, 2008 25
Figure 7: Top 20 Contract Research Organizations, Risk-Sharing Model Between Western Pharma Companies and Indian/Chinese Companies 28
Figure 8: Top 20 Contract Research Organizations, Fully Integrated Service Model 32
Figure 9: Top 20 Contract Research Organizations, Functional Service Model 33
Figure 10: Top 20 Contract Research Organizations, Global, CRO Market Forecasts ($bn), 2009–2017 35
Figure 11: Top 20 Contract Research Organizations, Revenue Analysis of Top Five Contract Research Organizations ($bn), 2008–2010 41
Figure 12: Top 20 Contract Research Organizations, Revenue Analysis of Top Ten Contract Research Organizations (%), 2009 42
Figure 13: Top 20 Contract Research Organizations, Revenue Analysis of Top Ten Contract Research Organizations (%), 2008-2010 43
Figure 14: Top 20 Contract Research Organizations, Quintiles, Snapshot, 2011 44
Figure 15: Top 20 Contract Research Organizations, Quintiles, Financial Performance ($bn), 2007-2009 48
Figure 16: Top 20 Contract Research Organizations, Quintiles, SWOT Analysis 49
Figure 17: Top 20 Contract Research Organizations, Covance, Snapshot, 2011 50
Figure 18: Top 20 Contract Research Organizations, Covance, 2008–2010 52
Figure 19: Top 20 Contract Research Organizations, Covance, SWOT Analysis 53
Figure 20: Top 20 Contract Research Organizations, Pharmaceutical Product Development, Snapshot, 2011 54
Figure 21: Top 20 Contract Research Organizations, Pharmaceutical Product Development, Financial Information, 2008–2010 59
Figure 22: Top 20 Contract Research Organizations, PPD, SWOT Analysis 60
Figure 23: Top 20 Contract Research Organizations, Charles River Laboratories, Snapshot, 2011 61
Figure 24: Top 20 Contract Research Organizations, Charles River Laboratories, 2008–2010 64
Figure 25: Top 20 Contract Research Organizations, CRL, SWOT Analysis 65
Figure 26: Top 20 Contract Research Organizations, PAREXEL, Snapshot, 2011 66
Figure 27: Top 20 Contract Research Organizations, PAREXEL, Financial Information, 2008–2010 69
Figure 28: Top 20 Contract Research Organizations, PAREXEL, SWOT Analysis 70
Figure 29: Top 20 Contract Research Organizations, ICON, Snapshot, 2011 71
Figure 30: Top 20 Contract Research Organizations, ICON, Financial Information, 2008–2010 73
Figure 31: Top 20 Contract Research Organizations, INC Research, Snapshot, 2011 74
Figure 32: Top 20 Contract Research Organizations, Kendle, Financial Information, 2008–2010 76
Figure 33: Top 20 Contract Research Organizations, PharmaNet Development Group, Snapshot, 2011 77
Figure 34: Top 20 Contract Research Organizations, PharmaNet, Financial Information, 2006–2008 79
Figure 35: Top 20 Contract Research Organizations, PRA International, Snapshot, 2011 80
Figure 36: Top 20 Contract Research Organizations, CMIC, Snapshot, 2011 82
Figure 37: Top 20 Contract Research Organizations, CMIC, Financial Information, 2008–2010 84
Figure 38: Top 20 Contract Research Organizations, Wuxi AppTec, Snapshot, 2011 85
Figure 39: Top 20 Contract Research Organizations, Wuxi AppTec, Financial Information, 2008–2010 87
Figure 40: Top 20 Contract Research Organizations, BioFocus, Snapshot, 2011 88
Figure 41: Top 20 Contract Research Organizations, Galapagos, Financial Information, 2008–2010 94
Figure 42: Top 20 Contract Research Organizations, LAB Research Inc, Snapshot, 2011 95
Figure 43: Top 20 Contract Research Organizations, LAB Research Inc, Financial Information, 2007–2009 96
Figure 44: Top 20 Contract Research Organizations, ReSearch Pharmaceutical Services, Snapshot, 2011 97
Figure 45: Top 20 Contract Research Organizations, ReSearch Pharmaceutical Services, Financial Information, 2007–2009 99
Figure 46: Top 20 Contract Research Organizations, Omnicare Clinical Research, Snapshot, 2011 100
Figure 47: Top 20 Contract Research Organizations, SGS, Snapshot, 2011 101
Figure 48: Top 20 Contract Research Organizations, United BioSource Corporation, Snapshot, 2011 102
Figure 49: Top 20 Contract Research Organizations, BioClinica, Snapshot, 2011 104
Figure 50: Top 20 Contract Research Organizations, BioClinica, Financial Information, 2008–2010 105
Figure 51: Top 20 Contract Research Organizations, Aptuit, Snapshot, 2011 106
Figure 52: Top 20 Contract Research Organizations, Chiltern, Snapshot, 2011 108
Figure 53: Top 20 Contract Research Organizations, Chiltern, Financial Information, 2008–2010 110

“Top 20 Contract Research Organizations (CRO) - Asia-Pacific, Especially India and China, Positioned to Benefit from Rising Financial and Regulatory Pressures in Western Pharmaceutical Markets” provides key data, information and analysis of leading CROs. The report provides a comprehensive insight into the CRO market size, and includes forecasts, profiles of top CROs, drivers and restraints and deals analysis.

Contract Research Organizations are Emerging as Strategic Partners

The pharmaceutical and biotechnology industry is currently forming strategic partnerships with contract research organizations in order to capitalize on their global presence and research expertise. Such agreements with contract research organizations are designed to improve the time to market and reduce costs. The service models of contract research organizations are evolving to become more functional, and now include services which are outsourced based on an analysis of their core competencies. The increasing focus on strategic partnerships will drive growth in emerging outsourcing destinations which have many small niche contract research organizations specializing in different functions. For example AstraZeneca formed clinical pharmacology alliance with Quintiles in 2009. AstraZeneca and Eli Lilly both extended such agreements with BioFocus. These partnerships help biopharmaceutical companies to reduce the time of approval by approximately one month and reduce costs by about 15–20%. Pharmaceutical companies will therefore rely on contract research organizations throughout the world to enhance the strength of their product pipeline by bringing drugs to approval faster.

Increasing Financial and Regulatory Pressures on Western Pharmaceuticals to Continue to Drive Drug Discovery Research Market Growth in India and China

The pharmaceutical industries in the US and Europe are facing severe financial constraints which are expected to worsen in the coming years. Pharmaceutical companies are under increasing pressure to reduce expenditure due to the increasing cost of introducing new molecular entities (NME), which in 2008 stood at more than $3 billion, tightening Food and Drug Administration (FDA) regulatory issues, blockbuster drugs worth more than $100 billion set to expire by 2014 and limited pipelines.

In an interview with GBI Research, Laurene Isip, Head of Corporate Communications at Covance Inc, said “Facing the loss of billions in annual sales due to key product patent expirations, many pharmaceutical companies are under significant pressure to cut costs. As a result, some companies have responded by restructuring their R&D organizations and others have looked to new outsourcing models, including alliances and partnerships with Contract Research Organizations (CROs), in order to develop a faster, more efficient drug development process.”

Such pressures are expected to encourage companies to perform R&D activities, a major expense, in low-cost countries such as India and China.

- Quintiles Transnational Corp.
- Covance
- Pharmaceutical Product Development
- Charles River Laboratories
- PAREXEL
- ICON
- INC Research
- PharmaNet Development Group Inc.
- PRA International
- CMIC
- WuXi AppTec
- Galapagos NV
- LAB Research Inc
- ReSearch Pharmaceutical Services
- Omnicare Clinical Research, Inc
- SGS
- United BioSource Corporation
- BioClinica
- Aptuit
- Chiltern

Note: Product cover images may vary from those shown

RELATED PRODUCTS

Our Clients

Our clients' logos