|
|
 |
|
Viewing report
|
|
|
|
Candida albicans. Edition No. 1
VDM Publishing House, April 2010, Pages: 164
Candida species are opportunistic yeasts that colonize the human body. Among the more well known and more virulent is Candida albicans. Although for several years, until 1995, another species, Candida dubliniensis, was mismatched with that one. Both Candida species possess similar phenotypic and genotypic characteristics. As this species has not been fully studied, it became important to understand its behaviour and its properties. Candida dubliniensis is mainly found in the mouth of some HIV patients. So, its behaviour in the oral cavity was chosen as the objective of the present work. The main goal of this work was the comparison of those two species in terms of the ability to adhere to inert surfaces and epithelial cells, to form biofilms and susceptibility to antifungal agents. The characteristics and behaviours under concern were assayed in two strains of each species. Artificial saliva solution was used in order to simulate the oral conditions. Yeast cells and inert surfaces were characterized in terms of physico-chemical surface properties as well as elemental surface composition determined by X-ray Photoelectron Spectroscopy.
|
|
|
|
