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Effects of Atomoxetine on Nicotine Abstinence
Symptoms. Edition No. 1
VDM Publishing House, Sep 2008, Pages: 100
One of the biggest public health problems worldwide
is nicotine dependence. Currently available FDA-
approved medications are successful in the treatment
of nicotine dependence for only a small subset of
smokers. Links between inattention and hyperactivity
symptoms and smoking have been identified both in
psychiatric and general populations. This book
describes a human behavioral pharmacology study
undertaken to evaluate the beneficial effects of the
ADHD medication atomoxetine on nicotine abstinence
symptoms. Smokers completed two 7-day medication
phases comparing initial efficacy of atomoxetine
(compared to placebo using double-blind design) on a
variety of self-report questionnaires, cognitive and
behavioral measures. Atomoxetine had beneficial
effects on self-report measures (after abstinence)
that are described in detail in this book. Such
human laboratory research examining effects of novel
medications on disease endophenotypes adds to the
highly exciting field of early medication
development in neuropsychiatry. This book would be
of keen interest to individuals from the fields of
psychiatry, neuroscience and behavioral
pharmacology.
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