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Viewing report
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ANDROGENS INDUCE GENDER-. Edition No. 1
VDM Publishing House, May 2009, Pages: 240
Cardiovascular disease (CVD) is the major cause of
morbidity and mortality in developed countries. Men
have a higher incidence and an earlier onset of CVD
than age-matched women. It has been shown that young
women have lower CVD incidence than young men and the
increasein CVD rates in older (post-menopausal) women
whenestrogen levels decline suggests that estrogens
are cardioprotective. This theory has been
extensively investigated demonstrating a favourable
reduction in LDL, reducing expression of cell
adhesion molecules and promoting vasodilatation by
inducing nitric oxide (NO) production in endothelial
cells. However, not many studies have explored the
alternate theory that male sex hormones, androgens (T
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