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A Common Virulence Plasmid in Eel-Pathogenic Vibrio vulnificus. Edition No. 1

VDM Publishing House, December 2008, Pages: 116

This is the first book describing the pathogenic
basis of biotype 2 Vibrio vulnificus in eels and
providing information that could be used in
developing strategies against V. vulnificus
infection in anguilliculture. The anguilliculture in
Asia and Europe has been threatened by this organism
for over 30 years. The eel is a kind of high-valued
fish and is unable to be artificially bred, which
makes V. vulnificus infections in anguilliculture a
cause of vast economic loss. In this research,
genetic approaches were employed to show that a
common plasmid present in all eel-pathogenic strains
is required for this pathogen to survive in the eel
blood and further kill the host. Moreover, this
plasmid can be disseminated with the help of another
plasmid.
Hor, Lien-I, Professor, National Cheng-Kung
University, Taiwan, said:
The exploration of virulence mechanisms of V.
vulnificus, an important opportunistic pathogen
causing severe systemic infections in both humans
and eels, is a continuing fascinating adventure. The
work accomplished in this study by collaborators in
Taiwan and Spain is a big step forward in this great
journey.

Chung-Te, Lee.
Ph.D. in Basic Medical Sciences at National Cheng-
Kung University, Taiwan. Postdoctoral fellow, Department of
Microbiology and Immunology, College of Medicine, National Cheng-
Kung University, Taiwan.