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Impedance-based Diagnostic Devices. Edition No. 1
VDM Publishing House, Jan 2009, Pages: 148
Percutanueous Transluminal Coronary Angioplasty
(PTCA) is a procedure used in modern medicine to
treat atherosclerotic plaque. Regretfully, not all
types of plaque are good candidates for this type of
procedure. If treated by PTCA, ‘unstable plaque’
could cause complications and lead to patients’ re-
hospitalization or even death. This book focuses
on the design of an impedance-based
device to diagnose unstable plaque. The proposed
system consists of an array of active
miniaturized piezoelectric sensors mounted on
a ‘smart’ angioplasty balloon and controlled by a
computer. A large scale ‘smart’ balloon, and the
manufacturing steps to miniaturize the device
are outlined. Numerical simulations and in vitro
tests clearly show that unstable plaque can be
diagnosed using the approach. Finally, examples of
the use of a ‘smart balloon’ device to induce cell
apoptosis, and the possibility to design impedance-
based devices for prostate cancer diagnosis are
addressed. This book is particularly recommended for
students and medical device professionals interested
in learning ‘hands-on’ the design and developing
process for novel diagnostic devices.
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