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Advances in computational protein design. Edition No. 1
VDM Publishing House, Feb 2009, Pages: 128
Protein design is the art of choosing an amino acid sequence that will fold into a desired structure. Computational protein design aims to quantify and automate this process. In computational protein design, various metrics may be used to calculate an energy score for a sequence with respect to a desired protein structure. An ongoing challenge is to find the lowest-energy sequences from amongst the vast multitude of sequence possibilities. A variety of exact and approximate algorithms may be used in this search.
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