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Carbohydrate-Modifying Biocatalysts

Pan Stanford Publishing Pte. Ltd, Sep 2011, Pages: 846


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This book provides an actual overview of structure, function, and application of carbohydrate-modifying biocatalysts. Unlike amino acids and nucleic acids, carbohydrates have been disregarded for a long time by the scientific community, mainly due to their complex structure and a lack of suited experimental methods for structure determination. Meanwhile, the situation changed with increasing knowledge about carbohydrates, glycoconjugates, and carbohydrate-modifying enzymes together with the key roles they play in biological processes such as recognition, signal transduction, and immune responses. An outcome of research activities in glycoscience, which, at the same time, is of great general interest, is the development of several new pharmaceuticals against serious diseases such as malaria, cancer, and various storage diseases.

Another important aspect, particularly against the background of the depletion of fossil fuels, above all oil, and the many problems related to the use of nuclear energy, is the employment of renewable raw materials, not only for future energy supply but also for the synthesis of chemicals, which is still oil-based to more than 70%. Here, carbohydrate-modifying biocatalysts, enzymes as well as microorganisms, will contribute significantly to the development of environmentally-friendly and, at the same time, cost-effective production processes, which are the main characteristics of White/Industrial Biotechnology.

key Features:

- The chapters impart the fundamental knowledge of properties of carbohydrate-modifying enzymes and microorganisms and discuss their application potential.
- Contributions are written by reckoned scientists, considering theoretical as well as experimental aspects of the respective research field. The articles represent the state-of-the-art of the treated topics.
- Each chapter is supplemented by an actual and comprehensive list of references for further reading.

Readership

Advanced undergraduate- and graduate-level students in chemistry, biology, biochemistry, and pharmacy; researchers (university, industry) in biology, chemistry, medicine, and pharmacy.

Reviews

This is an excellent compilation of the latest research in the field of carbohydrate-modifying biocatalysts written by highly recognized experts in the field. With glycoscience and biocatalysis emerging as fundamental contributors to a diverse array of scientific disciplines ranging from pharmaceutical development to renewable energy, this book is particularly timely and should serve as an excellent reference for inspiring scientists and students.

Prof. Jon S. Thorson - University of Wisconsin School of Pharmacy, USA



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