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Medicinal Chemistry of Nucleic Acids

John Wiley and Sons Ltd, Sep 2011, Pages: 456


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Complete, up-to-date coverage of the broad area of nucleic acid chemistry and biology.

Assembling contributions from a collection of authors with expertise in all areas of nucleic acids, medicinal chemistry, and therapeutic applications,' Medicinal Chemistry of Nucleic Acids' presents a thorough overview of nucleic acid chemistry - a rapidly evolving and highly challenging discipline directly responsible for the development of antiviral and antitumor drugs. This reliable resource delves into a multitude of subject areas involving the study of nucleic acids - such as the new advances in genome sequencing, and the processes for creating RNA interference (RNAi) based drugs - to assist pharmaceutical researchers in removing roadblocks that hinder their ability to predict drug efficacy.

Offering the latest cutting-edge science in this growing field, Medicinal Chemistry of Nucleic Acids includes:

- In-depth coverage of the development and application of modified nucleosides and nucleotides in medicinal chemistry
- A close look at a large range of current topics on nucleic acid chemistry and biology
- Essential information on the use of nucleic acid drugs to treat diseases like cancer
- A thorough exploration of siRNA for RNAi and the regulation of microRNA, non-coding RNA (ncRNA), a newly developing and exciting research area

Thorough in its approach and promising in its message, 'Medicinal Chemistry of Nucleic Acids' probes the new domains of pharmaceutical research—and exposes readers to a wealth of new drug discovery opportunities emerging in the dynamic field of nucleic acid chemistry.


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