Epidemiology: Non-Small Cell Lung Cancer - Despite global efforts to stop smoking, incidence rates will remain unchanged
Datamonitor, November 2011, Pages: 48
Smoking is the leading cause of lung cancer, responsible for 95% of all cases. Global efforts to stop smoking have stabilized over the last decade. Datamonitor epidemiologists expect the number of total incident cases of non-small cell lung carcinoma to remain stable in the seven major markets over the next 10 years.
Features and benefits
- Gain insight into market potential, including a robust 10-year epidemiology forecast of non-small cell lung cancer.
- Understand the key epidemiologic risk factors associated with non-small cell lung cancer.
Highlights
- Most people are not diagnosed with lung cancer until the disease has advanced to later-stage illness, making it difficult to treat the cancer successfully and greatly impacting 5-year survival rates for the disease. Smoking cessation is the most effective measure in reducing the risk of non-small cell lung cancer.
- For newly diagnosed non-small cell lung cancer in the seven major markets, adults aged 70–74 will have the largest number of total incident cases (80,310 cases), followed by adults ages 65–69 and 75–79 (73,500 cases and 71,300 cases, respectively).
Your key questions answered
- What are the most robust sources for non-small cell lung cancer incidence data?
- How will the patient population change through to 2020 in the US, Japan, and the five major EU markets (France, Germany, Italy, Spain, and the UK)?
- How do changes in population structure and risk factors affect the trend in incident non-small cell lung cancer cases?
Executive Summary
Disease background
Forecasted results
OVERVIEW
Catalyst
Summary
DISEASE DEFINITION AND DIAGNOSTIC CRITERIA
Overview of lung cancer
Classification of non-small cell lung cancer
Metastasis
Staging
Signs and symptoms of lung cancer
Diagnostic criteria for lung cancer
GLOBAL VARIATION AND HISTORICAL TRENDS
Incidence rates reflect exposure to tobacco smoke
Survival rates for lung cancer are the lowest of any cancer
Mortality rates are nearly equivalent to incident cases
Prevalence
DRIVERS OF NON-SMALL CELL LUNG CANCER EPIDEMIOLOGY
Up to 95% of lung cancer cases could be eliminated if smoking were eradicated
Other environmental factors may work synergistically with smoking to increase lung cancer risk
Current screening methods do not improve survival
Late presentation and diagnosis limit treatment options to surgery
EPIDEMIOLOGIC FORECASTING OF NON-SMALL CELL LUNG CANCER
Overview
Population denominators
Cancer registries: age- and sex-specific incidence rates
Subpopulations
Age
Stage
Description of methods
Statistical analysis
US
Japan
France
Germany
Italy
Spain
UK
EPIDEMIOLOGIC RESULTS
Diagnosed incident cases of lung cancer (all types)
The number of incident cases of lung cancer (all types) will remain stable from 2010 to
German men will have the highest age-standardized incidence rate of lung cancer (all types)
Segmentation of incident lung cancer cases (all types) in
Total incident cases of non-small cell lung cancer
The number of incident cases of NSCLC will remain stable from 2010 to
Spanish women will have the lowest age-standardized incidence rate of NSCLC
Segmentation of incident non-small cell lung cancer in
DISCUSSION
The strength of Datamonitor's epidemiologic projections
BIBLIOGRAPHY
Journal articles
Websites
APPENDIX
Module methodology
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