Progenitor and stem cell technologies and therapies

Woodhead Publishing Ltd, March 2012, Pages: 568

Progenitor and stem cells have the ability to renew themselves and change into a variety of specialised types, making them ideal materials for therapy and regenerative medicine. Progenitor and stem cell technologies and therapies reviews the range of progenitor and stem cells available and their therapeutic application. Part one reviews basic principles for the culture of stem cells before discussing technologies for particular cell types. Part two discusses wider issues such as intellectual property, regulation and commercialisation of stem cell technologies and therapies. The final part of the book considers the therapeutic use of stem and progenitor cells.

Part 1 Basic principles of stem cells: Basic principles for stem cell culture
- Basic principles of human embryonic stem cells
- Basic principles in generating induced pluirpotent stem cells
- Basic principles of amniotic and placental stem cells
- Basic principles of cord blood stem cells
- Basic principles of multipotent stem cells.

Part 2 Enabling cell therapy: Intellectual property claims to stem cell technologies: Research, clinical testing and product sales
- Regulatory considerations of stem and progenitor cell-based products: US Food and Drug Administration
- Cell therapy commercialisation
- Stem cell tourism.

Part 3 Tissue-specific progenitor cells: Adipose tissue-derived stem cell biology and therapy
- Umbilical cord blood (UCB) progenitor stem cell biology and therapy
- Auditory progenitor stem cell biology and therapy
- Olfactory mucosa: neural stem and progenitor cells for nervous system repair and cell models of brain disease
- Oral cavity progenitor and stem cell biology and therapy
- Bone marrow mesenchymal progenitor and stem cell biology and therapy
- Progenitor and stem cell therapies for cartilage repair
- Cardiac stem and progenitor cell biology and therapy
- Renal progenitor and stem cell biology and therapy
- Lung progenitor and stem cell biology and therapy
- Genitourinary progenitor and stem cell biology and therapy.

Anthony Atala is the W. Boyce Professor and Director of the Wake Forest Institute for Regenerative Medicine and the Chair of Urology at Wake Forest University, USA. Professor Atala is internationally recognised for his research in stem cells, tissue engineering and regenerative medicine.

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