• +353-1-415-1241(GMT OFFICE HOURS)
  • 1-800-526-8630(US/CAN TOLL FREE)
  • 1-917-300-0470(EST OFFICE HOURS)
Competitor Analysis: Novel Mitotic Kinase Inhibitors Product Image

Competitor Analysis: Novel Mitotic Kinase Inhibitors

  • Published: September 2011
  • Region: World
  • 62 Pages
  • La Merie Publishing

The present Competitive Intelligence Report about Novel Mitotic Kinase Inhibitors provides a competitor evaluation in the field of synthetic molecules targeting polo-like kinase 1 (Plk-1), cyclin-dependent kinase (CDK) or aurora kinase for treatment of cancer as of September 2011. Purchase of the downloadable pdf report includes a 6-month online access to the data of the report and any updates since the publication date. Credentials to access the database will be sent by e-mail and allow online work with the project data to print or export an individual report.

Mitosis, a central event in tumor growth, is highly regulated to ensure accurate and equal segregation of genetic materials from parent cells to daughter cells. Main effectors of this process are mitotic spindles and centrosomes.157 Disruption of the process results in aneuploidy, and genomic instability renders the cellular condition optimal for apoptosis to occur. The rationale of targeting mitosis in cancer therapy is substantiated by the successful clinical development of tubulin-disrupting agents, such as vinca alkaloids and taxanes.

The coordination of progression through mitosis is mainly orchestrated by READ MORE >

1. Novel Mitotic Kinase Inhibitors Cycline-dependent kinase (CDK1) inhibitors
Polo-Like Kinase 1 (Plk-1) Inhibitors
Plk-1 Inhibitors
Plk-2 Inhibitors Aurora Kinase Inhibitors
Selective Aurora A Kinase Inhibitors
Selective Aurora B Kinase Inhibitors
Dual Aurora B and C Kinase Inhibitors
Pan-Aurora Kinase Inhibitors
Dual- and Multi-Target Aurora Kinase Inhibitors

2. Corporate Novel Mitotic Kinase Inhibitors R&D Pipelines
ACT Biotech
Agennix
Amgen
Astex Therapeutics
AstraZeneca
Bayer HealthCare Pharmaceuticals
Boehringer Ingelheim
China Medical University
Chroma Therapeutics
Critical Outcome Technologies
Cyclacel Pharmaceuticals
Eli Lilly
EntreMed
Exelixis
GlaxoSmithKline (GSK)
Imperial College London
Johns Hopkins Medical Institution
Lead Discovery Center
Leukemia & Lymphoma Society (LLS)
Ligand Pharmaceuticals
ManRos Therapeutics
Marina Biotech
Merck & Co.
Merck Serono
Mount Sinai School of Medicine
Nerviano Medical Sciences
Novartis
Oncanova Therapeutics
Pfizer
Piramal Life Sciences
ProBioDrug
Rigel
S*Bio
Sanofi
Sareum
Selected Value Therapeutics
Sunesis Pharmaceuticals
Takeda Pharmaceutical Co.
Tekmira
The Institute of Cancer Research
Tragara Pharmaceuticals
TransTech Pharma
University of South Carolina
Telik

Format Properties
Electronic (PDF) The report will be emailed to you. The report is sent in PDF format. This is a single user license, allowing one specific user access to the product.
Site License The report will be emailed to you. The report is sent in PDF format. This is a site license, allowing all users within a given geographical location of your organisation access to the product.
Enterprisewide The report will be emailed to you. The report is sent in PDF format. This is an enterprise license, allowing all employees within your organisation access to the product.
Note: Product cover images may vary from those shown

RELATED PRODUCTS

Our Clients

Our clients' logos