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Epidemiology: Depression - A significant economic burden on society and the individual

Datamonitor, January 2012, Pages: 43

In 2011, it is estimated that there were 32.2 million 12-month prevalent cases of major depression those aged 18+ in the seven major markets. Due to stable prevalence rates of depression over the next decade, the number of cases will remain relatively stable.

Scope:

- Gain insight to market potential, including a robust 10-year epidemiology forecast of 12-month prevalent cases of major depressive disorder.
- Understand the key epidemiologic risk factors associated with major depressive disorder.

Highlights:

- Between 2011 and 2021, Datamonitor expects to see a very small increase in the number of 12-month prevalent cases of major depressive disorder in the seven major markets, from 32.2 million to 33.4 million. The largest number of and greatest increase in the number of cases will be in the US due to changes in population structure during this time.
- Datamonitor estimates that the greatest burden of major depressive disorder cases is in those aged 18–34, especially in women. In 2011, there were 4.4 million cases in men in this age group and 7.9 million cases in women in this age group.

Reasons to buy:

- What are the most robust sources for major depressive disorder prevalence data?
- How will the patient population change over the next decade in the US, Japan, and five major EU markets (France, Germany, Italy, Spain, and the UK)?
- How do changes in population structure and risk factors affect the trend in prevalent major depressive disorder cases?

OVERVIEW
Catalyst
Summary
EXECUTIVE SUMMARY
Epidemiology of major depressive disorder
Major depressive disorder in the seven major markets
Datamonitor’s forecast of major depressive disorder
DISEASE DEFINITION AND DIAGNOSIS CRITERIA
Disease definition and classification
Morbidity and mortality of major depressive disorder
GLOBAL VARIATION AND HISTORICAL TRENDS
An increase in prescriptions for major depression has not resulted in a large change in prevalence
Severity distribution of major depressive disorder cases
Data for children are not only difficult to ascertain but also may not be reliable
DRIVERS OF MAJOR DEPRESSIVE DISORDER
Risk factors
Age
Gender
Marital status
Unemployment or underemployment and income
Education
Disability and isolation
Personal experiences
Genetics
Co-morbidities
Anxiety disorders
Personality disorders
Impulse control disorders
Substance use disorders and smoking
Cardiovascular disease and stroke
EPIDEMIOLOGIC FORECASTING
Overview
Subpopulations
US
Sources used
Methods
Sources not used
Japan
Sources used
Methods
Sources not used
France
Sources used
Methods
Sources not used
Germany
Sources used
Methods
Sources not used
Italy
Sources used
Methods
Sources not used
Spain
Sources used
Methods
Sources not used
UK
Sources used
Methods
Sources not used
EPIDEMIOLOGIC RESULTS
Current prevalent cases of major depressive disorder and future trends
Age and gender
Age-standardized prevalence rates
DISCUSSION
Strengths and limits of Datamonitor’s epidemiologic projections
Conclusions
BIBLIOGRAPHY
Journal papers
Websites
Datamonitor reports
APPENDIX
Module methodology
TABLES
Table: ICD-10 and DSM-IV codes for major depressive disorder
Table: Severity distribution of major depressive disorder cases, by country
Table: Studies used to estimate 12-month prevalence of major depressive disorder in the seven major markets
Table: 12-month prevalent cases of major depressive disorder in adults aged 18 and over in the seven major markets (000s), 2011–
Table: 12-month p revalent cases of major depressive disorder in each of the seven major markets, by gender and age group (000s),
FIGURES
Figure: 12-month prevalent cases of major depressive disorder in adults aged 18 and over in the seven major markets (000s), 2011–
Figure: Age-standardized prevalence rates of major depressive disorder in the seven major markets, by gender,



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