0 CHECKOUT

Afinitor - A Two-Pronged Attack Against Tuberous Sclerosis Complex

  • ID: 2137713
  • May 2012
  • 5 pages
  • GlobalData

Afinitor - A Two-Pronged Attack Against Tuberous Sclerosis Complex

Summary

GlobalData’s new alert, "Afinitor - A Two-Pronged Attack Against Tuberous Sclerosis Complex”, takes a look at the implications of the FDA’s recent approval of the drug for the treatment of angiomyolipomas, benign kidney tumors that affect a majority of people with this rare disease.

This is the second indication for Afinitor in this patient population; in October 2010, the drug was approved for the treatment of a rare type of brain tumor in tuberous sclerosis complex (TSC) patients called subependymal giant cell astrocytoma (SEGA). The approval of Afinitor in a second indication for TSC means that the product is now available to fulfill an important unmet treatment need in this patient population.

Scope

- Introduction and detail on TSC and its consequences, including angiomyolipomas and SEGA
- Description of EXIST-2, the pivotal Phase III trial that established the efficacy and safety of Afinitor in treating angiomyolipomas in TSC patients
- Limitations of surgery and other current treatments for TSC patients with angiomyolipomas and SEGA

Reasons to buy

- Understand the therapeutic and market implications of the approval of Afinitor in its second indication in TSC
- Understand the market potential of Afinitor in additional cancer indications in the non-TSC population – specifically, advanced breast cancer in postmenopausal women.

Note: Product cover images may vary from those shown

1
1

2 Introduction
3 Afinitor - A Two-Pronged Attack Against Tuberous Sclerosis Complex
3.1 Tuberous Sclerosis Complex
3.2 Unmet Treatment Need in TSC
3.3 Phase III Trial of Afinitor in TSC Patients with Angiomyolipomas
3.4 Conclusions
4 Appendix
4.1 Methodology
4.1.1 Coverage
4.1.2 Secondary Research
4.1.3 Primary Research
4.1.4 Expert Panel Validation
4.2 Contact Us
4.3 Disclaimer

Note: Product cover images may vary from those shown
Note: Product cover images may vary from those shown

PLEASE SELECT A FORMAT

  • Quick Help: The report will be emailed to you. The report is sent in PDF format. This is a single user license, allowing one specific user access to the product.

  • Quick Help: The report will be emailed to you. The report is sent in PDF format. This is a site license, allowing all users within a given geographical location of your organisation access to the product.

  • Quick Help: The report will be emailed to you. The report is sent in PDF format. This is an enterprise license, allowing all employees within your organisation access to the product.

HAVE A QUESTION?

If you have a more general question about our products please try our

FAQ SECTION

RELATED PRODUCTS

Our Clients

  • Photocure ASA
  • Roche Diagnostics Ltd.
  • Abbott Laboratories Ltd.
  • Pfizer, Inc.
  • Novartis AG
  • Becton, Dickinson and Company (BD)