Clinical Research Updates - Drug Discovery
Euromed Communications Ltd, June 2012
Clinical Research Updates bring together guidance on everything to do with clinical trials, from pharmacokinetics and study design, to recruitment, monitoring, protection of subjects, statistics, budgeting ... all the compliance areas you need to conduct clinical trials that will conform to the regulations.
Written by some of the finest experts working in the clinical trials field, Clinical Research Updates translate regulations and best practices into real-world guidance. Both new and experienced trial managers will find the information they need to set up and run every phase of a clinical research program -- from drug discovery through postmarketing surveillance -- in the US or abroad.
Focusing on the US, Europe and Asia, Clinical Research Updates have been updated in 2012 to make it the most current and comprehensive resource available
Introduction
Genomics and new target discovery
Defining a new drug discovery project
Leads with an unknown mode of action
Natural products as leads
Target Considerations
High throughput screening
Developments in compound collections
Fragment Screening
Optimisation of preclinical properties
Computational Chemistry and Chemoinformatics
Some important small molecule target families
Protein-protein interactions
Drug delivery
Chemogenomics
Conclusions
References
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