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Susceptibility Weighted Imaging in MRI. Basic Concepts and Clinical Applications

  • ID: 2174603
  • Book
  • November 2011
  • 760 Pages
  • John Wiley and Sons Ltd
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This book presents the first in–depth reference to discuss Susceptibility Weighted Imaging for students and professionals

Within the pages of this book, the reader will find comprehensive coverage of the major concepts that underlie the origins of susceptibility weighted imaging (SWI) in magnetic resonance imaging (MRI) and its wide range of applications. This book provides readers a thorough understanding of the technique now commonly called SWI, a major enhancement of traditional MRI with the power to produce high–resolution images that are exquisitely sensitive to blood products and iron. Since its inception, SWI has become a powerful tool for investigating a number of important clinical aspects of neuro–imaging, especially the diagnosis and pathophysiology of traumatic brain injury, the detection of acute hemorrhagic stroke, and the detection of microbleeds in dementia.

Edited by the originators of SWI, this groundbreaking text is the definitive resource on this critically important technology. Featuring contributions from the top leaders in the science and clinical use of the modality, the book:

  • Introduces the fundamentals of SWI

  • Presents an even balance between the technical aspects and its clinical applications

  • Explains how to image brain tumors, cerebral microbleeds, and hemorrhage as well as many other clinical applications

  • Explains how to quantify iron content for diseases such as multiple sclerosis, Parkinson′s disease, and other neurodegenerative diseases

  • Introduces the use of SWI in visualizing the vessel wall

  • Covers the use of SWI at ultra–high magnetic fields

  • Introduces the important concept of susceptibility mapping as the next generation of SWI

  • Includes over 100 high–quality images and tables

This reference also covers more advanced topics, from improved contrast in MRI of the midbrain using SWI to functional susceptibility weighted MRI, automated vein segmentation and lesion detection, rapid acquisition methods, and more.

Suitable for all levels of experience, Susceptibility Weighted Imaging in MRI is the ideal source for neuroradiologists, radiologists, imaging and medical physicists, cardiologists, oncologists, biochemists, and students who want authoritative information on the basic elements and practical applications of this exciting new medical imaging technique.

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Part I Basic Concepts.

1 Introduction to Susceptibility Weighted Imaging (Jürgen R. Reichenbach and E. Mark Haacke).

2 Magnetic Susceptibility (Jaladhar Neelavalli and Yu–Chung Norman Cheng).

3 Gradient Echo Imaging (Jürgen R. Reichenbach and E. Mark Haacke).

4 Phase and Its Relationship to Imaging Parameters and Susceptability (Alexander Rauscher, E. Mark Haacke, Jaladhar Neelavalli, and Jürgen R. Reichenbach).

5. Understanding T2–Related Signal Loss (Jan Sedlacik, Alexander Rauscher, Jürgen R. Reichenbach, and E. Mark Haacke).

6 Processing Concepts and SWI Filtered Phase Images (Alexander Rauscher and Stephen Witoszynskyj).

7 MR Angiography and Venography of the Brain (Samuel Barnes, Zhaoyang Jin, Yiping P. Du, Andreas Deistung, and Jürgen R. Reichenbach)

8 Brain Anatomy with Phase (Jeff Duyn and Oliver Speck).

Part II Current Efforts in Clinical Translational Research Using SWI.

9 SWI Venography Anatomy of the Cerebrum (Daniel K. Kido, Jessica Tan, Steven Munson, Udochukwu E. Oyoyo, and J. Paul Jacobson).

10 Novel Approaches to Imaging Brain Tumors (Sandeep Mittal, Bejoy Thomas, Zhen Wu, and E. Mark Haacke).

11 Traumatic Brain Injury (Karen Tong, Barbara Holshouser, and Zhen Wu).

12 Imaging Cerebral Microbleeds with SWI (Muhammad Ayaz, Alexander Boikov, Grant McAuley, Mathew Schrag, Daniel K. Kido, E. Mark Haacke and Wolff Kirsch).

13. Imaging Ischemic Stroke and Hemorrhage with SWI (Nathaniel Wycliffe, Guangbin Wang, MasahiroIda, and Zhen Wu).

14 Visualizing Deep Medullary Veins with SWI in Newborn and Young Infants (J. Paul Jacobson, Udiochukwu E. Oyoyo, Daniel K. Kido, John Wuchenich, and Stephen Ashwal).

15 Susceptibility Weighted Imaging in Multiple Sclerosis (Yulin Ge, Robert I. Grossman, and E. Mark Haacke).

16 Cerebral Venous Diseases and Occult Intracranial Vascular Malformations (Hans–Joachim Mentzel, Guangbin Wang, Masahiro Ida, and Jürgen R. Reichenbach).

17 Sturge–Weber Syndrome (Zhifeng Kou, Csaba Juhasz and Jiani Hu).

18 Visualizing the Vessel Wall Using Susceptibility Weighted Imaging (Yang Qi, Samuel Barnes and E. Mark Haacke).

19 Imaging Breast Calcification Using SWI (Michael D. Noseworthy, Colm Boylan, and Ali Fatemi–Arkekani).

20 Susceptibility Weighted Imaging at Ultrahigh Magnetic Fields (Andreas Deistung, Samuel Barnes, Yulin Ge, and Jürgen R. Reichenbach).

Part III Advanced Concepts.

21. Improved Contrast in MR Imaging of the Midbrain Using SWI (Elena Manova and E. Mark Haacke).

22. Measuring Iron Content with Phase (Manju Liu, Charbel Habib, Yanwei Miao, and E. Mark Haacke).

23 Validation of Phase Iron Detection with Synchrotron X–Ray Fluorescence (Helen Nichol, Karla Hopp, Bogdan F. Popescu, and E. Mark Haacke).

24 Rapid Calculation of Magnetic Field Perturbations from Biological Tissue in Magnetic Resonance Imaging (Jaladhar Neelavalli, Yu–Chung Norman Cheng, and E. Mark Haacke).

25 SWIM: Susceptibility Mapping as a Means to Visualize Veins and Quantify Oxygen Saturation (Jin Tang, Jaladhar Neelavalli, Saifeng Liu, Yu–Chung Norman Cheng, and E. Mark Haacke).

26 Effects of Contrast Agents in Susceptibility Weighted Imaging (Andreas Deistung and Jürgen R. Reichenbach).

27 Oxygen Saturation: Quantification (E. Mark Haacke, Karthik Probhakaran, Ilaya Raja Elangovan, Zhen Wu, and Jaladhar Neelavalli).

28 Quantification of Oxygen Saturation of Single Cerebral Veins, the Blood Capillary Network, and Its Dependency on Perfusion (Jan Seldlacik, Song Lai, and Jürgen R, Reichenbach).

29. Integrating Perfusion Weighted Imaging, MR Angiography, and Susceptibility Weighted Imaging (Meng Li and E. Mark Haacke).

30 Functional Susceptibility Weighted Magnetic Resonance Imaging (Markus Barth and Daniel B. Rowe).

31 Complex Thresholding Methods for Eliminating Voxels That Contain Predominantly Noise in Magnetic Resonance Images (Daniel R. Rowe, Jing Jiang, and E. Mark Haacke).

32 Automatic Vein Segmentation and Lesion Detection: from SWI–MIPs to MR Venograms (Samuel Barnes, Markus Barth and Peter Koopmans).

33 Rapid Acquisition Methods (Song Lai, Yingbiao Xu and E. Mark Haacke).

34 High–Resolution Venographic  BOLD MRI of Animal Brain at 9.4 T: Implications for BOLD fMRI (Seong–Gi Kim and Sung–Hong Park).

35 Susceptibility Weighted Imaging in Rodents (Yimin Shen, Zhigeng Kou, and E. Mark Haacke).

36 Ultrashort TE Imaging: Phase and Frequency Mapping of Susceptibility Effects in Short T2 Tissues of the Musculoskeletal System (Jiang Du, Michael Carl, and Graeme M. Bydder) .

Appendix: Seminal Articles Related to the Development of Susceptibility Weighted Imaging.


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"Presenting an even balance between technical/scientific aspects of the modality and clinical application, this book includes over 100 super high–quality radiographic images and 100 additional graphics and tables." (Financial Technology, 16 March 2011)
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Note: Product cover images may vary from those shown