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Modern Biopharmaceuticals. Recent Success Stories

  • ID: 2179896
  • April 2013
  • 800 Pages
  • John Wiley and Sons Ltd

This collection of high-profile contributions provides a unique insight into the development of novel, successful biopharmaceuticals.

Outstanding authors, including Nobel laureate Robert Huber as well as prominent company researchers and CEOs, present valuable insider knowledge, limiting their scope to those procedures and developments with proven potential for the biotechnology industry. They cover all relevant aspects, from the establishment of biotechnology parks, the development of successful compounds and the implementation of efficient manufacturing processes, right up to the establishment of advanced delivery routes.

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MODERN BIOPHARMACEUTICALS: RESEARCH IS THE BEST MEDICINE - SANITAS SUMMUM BONUS

Twenty Thousand Years of Biotech - from "Traditional" to "Modern" Biotechnology (Jörg Knäblein)

MODERN BIOPHARMACEUTICAL DEVELOPMENT USING STEM CELLS, TISSUES, AND WHOLE ANIMALS

Induced Pluripotency as Substitute of Somatic Cell Nuclear Transfer? - The Impact of Induced Pluripotent Stem Cells on Drug Discovery and Regenerative Biopharmaceuticals (Miodrag Stojcovic, Rita P. Cervera)

Pluripotent Stem Cell-Derived Cardiomyocytes for Industrial and Clinical Applications (Wolfram-H. Zimmermann, James E. Hudson, Peter Christalla)

Industrialization of Functional Mouse Genomics for Biopharmaceutical Development (Peter Stadler, Jost Seibler, Frieder Schwenk)

INNOVATIVE DEVELOPMENT TOOLS FOR MODERN BIOPHARMACEUTICALS

Standardized Solutions for Quantitative Real-time PCR to Accelerate Biopharmaceutical Development (Dirk Löffert)

Massive Mutagenesis: The Path to Smarter Genetic Libraries for Effective Biopharmaceuticals (Julien Sylvestre, Stéphane Blesa, Ingrid Marchal, Philippe Thulier, Olivier Dubreuil, Marc Delcourt)

Cut & Go - FastDigest With All Restriction Enzymes atsame Temperature and Buffer: A New Paradigm in DNA Digestion to Speed-up Biopharmaceutical Development (Arvydas Janulaitis)

StarGate: A high capacity expression cloning system to speed up biopharmaceutical development (Thomas G.M. Schmidt, Uwe D. Carl, Lilia Batz, Isabel Schuchardt, Lothar Germeroth)

Precision Genome Surgery With Meganucleases: A Promising Biopharmaceutical for Gene Therapy (Alfred Pingoud, George H. Silva, Wolfgang Wende)

Innovative Diagnostics Enhance and Advance the Impact of in vivo Small Animal Imaging in Drug Discovery and Pharmaceutical Development (Andreas Briel)

Revolutionizing Biopharmaceutical Development with Quantitative Multi-spectral Opto-acoustic Tomography (MSOT) (Vasilis Ntziachristos, Daniel Razansky)

Research Biobanking: Need, Socioethical Considerations, and Best Practise (Arndt A.P. Schmitz, Janine Swifka, Khusru Asadulla)

THE RISE OF MONOCLONAL ANTIBODIES - THE PREMIUM CLASS OF BIOPHARMACEUTICALS

Implementation of Current Advanced Technology in Commercial Mab Production (Joe Zhou, Tim Tressel, Xiaoming Yang, Thomas Seewoester)

Plantibodies for Human Therapeutic Use (Jörg Knäblein, Merardo Pujol, Carlos Borroto)

SMART SOLUTIONS FOR GLOBAL CHALLANGES - VACCINE-BASED BIOPHARMACEUTICALS

A Modern Biopharmaceutical to Treat AIDS - Challenges in Designing HIV Env Immunogens for Developing a Vaccine (Indresh Srivastava, Zohar Biron)

Superfast Biopharmaceutical Development - Vero Cell technology and Pandemic Influenza Vaccine Production (P. Noel Barrett, Daniel Portsmouth, Hartmut J. Ehrlich)

MODERN BIOPHARMACEUTICALS - THE HOLY GRAIL FOR HEALTH AND WEALTH

BioBenchmarking: the Global Perspective to Ensure Future Success of Biopharmaceutical Development (Pete Caldwell)

Medicinal Biotechnology - A European Snapshot of Biopharmaceutical Use in Germany (Axel Heinemann, Sabine Sydow)

Experience with Omnitrope, the first ever Approved Similar Biopharmaceutical Product (Alexander Berghout, Andreas Premstaller, Marc McCamish)

Recombinant Factor VIII (Kogenate) for the Treatment of Hemophilia A: The first and only world-wide Licensed Recombinant Protein Produced in High-Throughput Perfusion Culture (Berthold G. D. Boedeker)

FROM INNOVATIVE TOOLS TO IMPROVED THERAPIES - THE SUCCESS OF SECOND-GENERATION BIOPHARMACEUTICALS

Post-translational Modifications to Improve Biopharmaceuticals (Gary Walsh)

High-throughput Biomaterials-mediated Delivery of DNA and siRNA Biopharmaceuticals (Robert Langer, Fan Yang, Michael Goldberg, Daniel G. Anderson)

BIOPHARMACEUTICAL MANUFACTURING AND DOWNSTREAM PROCESSING - HOW TO UNCORK BOTTLENECKS

Bright Future Outlook and Huge Challenges to Overcome: An attempt to Write the Short Story of the Biopharma Industry with Current Status, Selected Issues, and Potential Solutions in Discovery, R&D, and Manufacturing (Günter Jagschies)

Large Scale Manufacturing of Biopharmaceuticals: Speed up the Road to Market - 6x 15,000 liter BI Bioreactors (Andreas Werner)

Large Scale Purification of Biopharmaceuticals by Affinity Tag (Frank Schäfer, Conni Lauritzen, Gitte E. Petersen, John Pedersen, José Arnau, Ulla Römer)

In-situ On-line Monitoring of Fermentation Processes: A Cool Tool for Biopharmaceutical Production (Oscar Reif, Reinhard Baumfalk, Ina Pahl)

Queen Honeybee & Me: Forever Young? Conserved Pathways for Longevity (Jörg Knäblein, Robert Huber)

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Dr. Jörg Knäblein studied Biotechnology / Chemical Engineering at the Society for Biotechnology Research (GBF) in Braunschweig, Germany and Biochemistry at the Max-Planck-Institute for Biochemistry. He received his Ph.D. from the Max-Planck-Institute for Biochemistry in Martinsried / Munich where he worked in the group of Professor Robert Huber (Nobelprize laureate in 1988). Jörg Knäblein holds a leading position in technology scouting at Bayer Schering Pharma AG, Berlin.. . . AWARDS:. Riedel-de Haen-Stiftung. Government / Ministry of Science. Nomination for the Max-Buchner-Award from DECHEMA (Society for Biotechnology and Chemical Engineering). Winner of the McKinsey business plan contest

Note: Product cover images may vary from those shown
Note: Product cover images may vary from those shown

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