Epidemiology: Asthma in China – Aging population and rising urbanization increase asthma prevalence

Datamonitor, June 2012, Pages: 36

Overview of asthma prevalence in China and a review of epidemiology literature. This report provides in-depth analysis of patient populations, a 10-year prevalent case forecast, and key patient segments across the seven major markets.

In this report, Datamonitor estimates that there were a total of 18.5 million cases of asthma in 2011 in China, with the majority (79%) living in urban areas. Prevalence rates are expected to remain constant, although the total number of cases will increase as a result of the aging population and increasing urbanization.

Scope

- Gain insight into market potential, including a robust 10-year epidemiology forecast of prevalent asthma cases.

- Understand the key epidemiologic risk factors associated with asthma.

Highlights

- Datamonitor estimates that there were approximately 18.5 million asthmatics in China in 2011. Between 2011 and 2021, asthma prevalent cases will increase by approximately 17% nationally. The number of cases will increase by 37% in urban areas, but will decline by 58% in rural areas.

- Datamonitor estimates that tier one and two cities in China had approximately 2.07 million and 4.05 million cases, respectively, in 2011.

Reasons to Purchase

- What are the most robust epidemiologic studies for asthma prevalence data?

- How will the patient population change over the next decade in China?

- How do changes in population structure and risk factors affect the trend in prevalent asthma cases?

OVERVIEW

- Catalyst
- Summary

EXECUTIVE SUMMARY

- Asthma epidemiology
- Asthma in China
- Datamonitor’s forecast of asthma epidemiology

DISEASE DEFINITION AND DIAGNOSIS CRITERIA

- Asthma background
- Case identification

GLOBAL VARIATION AND HISTORICAL TRENDS

- Contemporary trends
- Asthma prevalence varies by gross national income
- Asthma remains largely under-diagnosed
- Urban asthma prevalence remains significantly higher than rural rates
- Asthma causes a large burden, a high number of disability-adjusted life years, and mortality worldwide?Disease burden

DRIVERS OF ASTHMA EPIDEMIOLOGY

- Genetic and environmental factors are strongest risk factors
- - Genetic factors and atopy aggravated in presence of environmental allergens
- - Environmental factors triggered the recent increase in asthma prevalence worldwide

- Lifestyle-related factors
- - Smoking: in utero exposure presents the highest risk of asthma
- - Body weight: extreme underweight and overweight patients are at higher risk

- Demographic characteristics
- - Age and gender: more prevalent in males in childhood, yet increasingly prevalent in females after puberty

- Co-morbid conditions
- - Asthma and COPD can be confused in diagnosis
- - Allergic rhinitis is the most common co-morbidity
- - Gastroesophageal reflux disease treatment greatly improves asthma symptoms

EPIDEMIOLOGIC FORECASTING OF ASTHMA IN CHINA

- Sources of epidemiologic data
- - Population denominators
- - Asthma severity

- Description of methods?Sources used: tier one cities
- - Methods
- - Sources used: tier two cities
- - Methods
- - Sources used: national data
- - Sources used: rural and urban data
- - Methods

EPIDEMIOLOGIC FORECAST RESULTS

- Estimated asthma prevalence cases
- - National estimates
- - Rural and urban estimates
- - Tier one cities estimates
- - Tier two cities estimates
- - Estimating asthma cases by severity
- - Age and gender
- - Age-standardized prevalence rates

DISCUSSION

- Strengths and limitations of Datamonitor's epidemiologic projections

BIBLIOGRAPHY

- Journal articles
- Websites

TABLES

Table: ICD-10 codes associated with asthma
Table: Asthma prevalence rate studies from multi-country, cross-sectional surveys
Table: Asthma prevalence rate studies in South East Asia
Table: Asthma case fatality rates, deaths per 100,000 asthmatics in the 5–34 age group
Table: Economic indicators in Chinese city tiers, 2005
Table: Summary of sources used in this forecast
Table: Global Initiative for Asthma guidelines on severity
Table: Total prevalent cases of current asthma in all ages in China (000s), 2011–21
Table: Total prevalent cases of current asthma in China, by severity (000s), 2011
Table: Total prevalent cases of current asthma in China, by age group (000s), 2011

FIGURES

Figure: Worldwide prevalence of clinical asthma
Figure: Relationship between BMI (kg/m 2 ) and risk of asthma in Anqing, China
Figure: Proportion of population living in urban areas in China, 1950–2020
Figure: Total prevalent cases of current asthma in all ages China (000s), 2011–21
Figure: Total prevalent cases of current asthma in tier one cities, China (000s), 2011–21
Figure: Total prevalent cases of current asthma in China, by gender (000s), 2011
Figure: Age-specific prevalent cases of asthma in China (000s), 2011–21
Figure: Age-standardized prevalence rates of current asthma in China, by gender, 2011

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