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Shire plc: PharmaVitae Report

Datamonitor, July 2012, Pages: 41

Analysis of Shire's corporate strategy, marketed portfolio, pipeline potential and financial position in 2011 and to 2017

This analysis examines the historical and forecast performance for Shire in the prescription pharmaceutical sector. The profile encompasses global company strategy, portfolio and pipeline analysis and assessment of financial performance, with 1-6 year sales forecasts for key drugs

Scope

- Gain insight into Shire's strategic outlook across the next 6 years
- Analyze company sales forecasts by product, therapy area, lifecycle stage, geography, molecule type and source

Highlights

- Shire exhibited rapid revenue growth over 2005–11, despite a dip in sales over 2008–09 caused by generic erosion to Adderall XR. Shire’s impressive performance has been driven not only by its effective lifecycle management strategy, but also by strong uptake of its Human Genetic Therapies portfolio.

- During the forecast period, Shire is expected to see a slowdown in sales growth. This is largely attributable to the absence of new product launches in the near future, given that its R&D pipeline is largely based on early-stage products.

Reasons to Purchase

- Benchmark Shire's performance against key rivals in the prescription pharmaceutical sector
- Assess how successful Shire will be in diversifying its business focus and reducing its reliance on the US ADHD market
- See how Shire has developed a portfolio of products indicated for highly symptomatic diseases in an effort to build sustainable growth

SCOPE OF SHIRE ANALYSIS
- PharmaVitae Explorer database
- Analysis structure
- - Strategic Insight
- - Company Overview
- - Operating Performance Analysis

EXECUTIVE SUMMARY
- Key findings
- Shire prescription pharmaceutical sales outlook
- Shire financial outlook
- SWOT analysis
- - Weaknesses
- - Opportunities
- - Threats

STRATEGIC INSIGHT
- Key findings
- Launch/core/expiry analysis
- Strategic insight
- - Despite a declining focus in CNS, this therapy area will continue to generate the majority of sales out to 2017
- - Niche disorders to be Shire’s other key area of sales growth
- - Generic competition in CNS market justifies switch in focus to niche disorders

CORPORATE STRUCTURE
- Key findings
- Background
- Corporate structure
- - Human Genetic Therapies
- - Specialty Pharmaceuticals
- - Regenerative Medicine

- M&A history
- - M&A strategy

OPERATING PERFORMANCE
- Key findings
- Reconciliation between PharmaVitae-formatted prescription pharma sales and company-reported total sales, 2005–11
- Operating costs and profit analysis
- - Operating costs and profit analysis, 2005–11
- - Operating cost ratio and profit margin analysis, 2005–11
- - Operating cost ratio and profit margin analysis, 2011–17
- - Operating costs and profit analysis, 2011–17

APPENDIX
- References
- Exchange rates

TABLES

Table: Datamonitor’s established pharmaceutical company coverage, 2012
Table: Shire – key product overview ($m), 2011–17 Table: Shire’s financial performance ($m), 2011–17
Table: Shire’s launch, core, and expiry portfolio overview ($m), 2011–17
Table: The Gaucher disease market, 2012
Table: Shire’s key merger and acquisition deals, 1995-12
Table: Total Shire sales by business unit ($m), 2005–11
Table: Shire’s operating revenue/cost analysis ($m), 2005–11
Table: Shire’s operating cost ratio analysis (percentage of total revenues), 2005–11
Table: Shire’s operating cost ratio analysis (percentage of total revenues), 2011–17
Table: Shire’s operating revenue/cost analysis ($m), 2011–17
Table: Exchange rates, 2012

FIGURES

Figure: The PharmaVitae Explorer
Figure: Shire’s prescription pharmaceutical performance, sales ($m) and growth rate (%), 2005–17
Figure: Shire’s financial performance ($m), 2005–17
Figure: Shire’s launch/core/expiry configuration ($m), 2011–17
Figure: Shire’s prescription pharmaceutical sales, by therapy area ($m), 2003–17
Figure: Forecast sales of the Gaucher disease drug market ($m), 2011–17
Figure: Shire’s corporate structure
Figure: Shire’s operating revenue/cost analysis ($m), 2005–17

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