Ataxic Disorders, Vol 103. Handbook of Clinical Neurology
Elsevier Science and Technology, September 2011, Pages: 680
This volume's primary goal is to provide a comprehensive understanding of recent developments and advancements in the study of ataxic disorders. Beginning with an examination of the cerebellar region, and then progressing to a fresh perspective on the clinical aspects of the various forms of ataxia, this handbook gives clinicians a state-of-the-art reference for the management of the many etiologies and neurological manifestations of ataxic disorders.
Clinicians will gain a broader understanding of generative ataxias and the genetic disorders associated with them. In addition, new neurophysiological and imaging techniques are discussed, along with an in-depth examination of the treatment and management protocols of ataxic diseases.
A volume in the Handbook of Clinical Neurology series, which has an unparalleled reputation as the world's most comprehensive source of information in neurology.
International list of contributors including the leading workers in the field.
Describes the advances which have occurred in clinical neurology and the neurosciences, their impact on the understanding of neurological disorders and on patient care.
BASIC ASPECTS The cerebellum
structure and connections
Physiology of clinical dysfunction of the cerebellum
Oculomotor aspects of the hereditary cerebellar ataxias
Magnetic resonance and nuclear medicine imaging studies in ataxic disease
Neuropathology of degenerative ataxias
Approach to ataxic diseases
ACQUIRED ATAXIAS Acquired ataxias, infectious and para-infectious
Ataxia in patients with brain infarcts and hemorrhages
Ataxia resulting from posterior fossa tumors of childhood and other mass lesions; Nutritional cerebellar degeneration, with comments on its relationship to Wernicke disease and alcoholism
Immune-mediated acquired ataxias
Toxic agents causing cerebellar ataxias
Paraneoplastic cerebellar degeneration
DEGENERATIVE ATAXIAS Epidemiology and population genetics of degenerative ataxias
Sporadic adult onset ataxia of unknown aetiology
DEGENERATIVE ATAXIAS
MITOCHONDRIAL, AUTOSOMAL RECESSIVE AND X-LINKED Overview of autosomal recessive ataxias
Friedrich's ataxia
Ataxia with vitamin E deficiency and abetalipoproteinemia
Ataxia-telangiectasia
Autosomal recessive cerebellar ataxias with oculomotor apraxia
Other autosomal recessive and childhood ataxias
Ataxia in mitochondrial disorders
Fragile X-associated tremor/ataxia syndrome
DEGENERATIVE ATAXIAS
AUTOSOMAL DOMINANT Overview of autosomal dominant ataxias
Spinocerebellar ataxia type 1, 2
Machado-Joseph disease/spinocerebellar ataxia type 3
Spinocerebellar ataxia type 5, 6, 7
Clinical and genetic features of spinocerebellar ataxia type 8
Spinocerebellar ataxia type 10, 11, 12, 13, 14, 15, 20, 25, 28
Other spinocerebellar ataxias
Dentatorubral-pallidoluysian atrophy
Episodic ataxias 1 and 2
OTHER ISSUES Ataxias related to sensory neuropathies
Frontal lobe ataxia
Balance and gait problems in the elderly
Treatment and management issues in ataxic disease
Subramony, Sankara H.
Dürr, Alexandra
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